Classification des carcinomes thyroïdiens de souche folliculaire: classification histologique, altérations génomiques, classification pronostique

Classification of thyroid cancer of follicular origin. The 2017-WHO histological classification individualizes 4 groups of differentiated thyroid cancer of follicular origin: papillary the most frequent with several subtypes, follicular, oncocytic and poorly differentiated. This histological classification is closely related to genomic abnormalities found in these cancers. Initial estimate of the risk of cancer related death is based on the TNM classification and that of the risk of recurrence on the American Thyroid Association stratification; these two risk estimates will guide the extent of initial treatment. Then, a dynamic classification that can be modified at each work-up will appreciate the tumoral status and thus the risk of recurrence and of cancer related death.