CMML: Clinical and molecular aspects

Raphael Itzykson; Matthieu Duchmann; Nolwenn Lucas; Eric Solary

doi:10.1007/s12185-017-2243-z

CMML: Clinical and molecular aspects

Raphael Itzykson, Matthieu Duchmann, Nolwenn Lucas, Eric Solary

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

35 Citations (Scopus)

Résumé

Chronic Myelomonocytic Leukemia is a chronic myeloid neoplasm occurring mostly in the elderly with overlapping features of myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) characterized by chronic monocytosis. Recent progresses in the molecular and cellular pathogenesis of CMML have stirred a renewed interest in this clinically heterogeneous disorder. Here, we review the recent progresses in the biology of CMML and how it affects its current and future clinical management.

langue originale	Anglais
Pages (de - à)	711-719
Nombre de pages	9
journal	International Journal of Hematology
Volume	105
Numéro de publication	6
Les DOIs	https://doi.org/10.1007/s12185-017-2243-z
état	Publié - 1 juin 2017

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10.1007/s12185-017-2243-z

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abstract = "Chronic Myelomonocytic Leukemia is a chronic myeloid neoplasm occurring mostly in the elderly with overlapping features of myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) characterized by chronic monocytosis. Recent progresses in the molecular and cellular pathogenesis of CMML have stirred a renewed interest in this clinically heterogeneous disorder. Here, we review the recent progresses in the biology of CMML and how it affects its current and future clinical management.",

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AU - Lucas, Nolwenn

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