TY - JOUR
T1 - Combined retinol-lactose-glycolic acid effects on photoaged skin
T2 - A double-blind placebo-controlled study
AU - Bertin, C.
AU - Zunino, H.
AU - Lanctin, M.
AU - Stamatas, G. N.
AU - Camel, E.
AU - Robert, C.
AU - Issachar, N.
PY - 2008/6/1
Y1 - 2008/6/1
N2 - The objective of this study was to assess the efficacy of the combination of retinol, lactose and glycolic acid applied topically on photodamaged skin. Forty female volunteers were enrolled in a double-blind, randomized placebo-controlled clinical study. A cream containing retinol, lactose and glycolic acid was applied on one side of the face and a placebo cream on the other side, twice daily for 12 weeks. Skin photoageing signs were assessed clinically, whereas skin microrelief and moisturization were measured instrumentally. Both the clinical assessment and the objective instrumental measurements revealed that the active-treated side was significantly improved at the end of the study compared with baseline and control-treated side. In conclusion, our results demonstrate that topical application of a combination of retinol, lactose and glycolic acid has significantly improved the appearance of photodamaged skin.
AB - The objective of this study was to assess the efficacy of the combination of retinol, lactose and glycolic acid applied topically on photodamaged skin. Forty female volunteers were enrolled in a double-blind, randomized placebo-controlled clinical study. A cream containing retinol, lactose and glycolic acid was applied on one side of the face and a placebo cream on the other side, twice daily for 12 weeks. Skin photoageing signs were assessed clinically, whereas skin microrelief and moisturization were measured instrumentally. Both the clinical assessment and the objective instrumental measurements revealed that the active-treated side was significantly improved at the end of the study compared with baseline and control-treated side. In conclusion, our results demonstrate that topical application of a combination of retinol, lactose and glycolic acid has significantly improved the appearance of photodamaged skin.
KW - Glycolic acid
KW - Lactose
KW - Photoageing
KW - Retinol
KW - Skin ageing
UR - http://www.scopus.com/inward/record.url?scp=43049135504&partnerID=8YFLogxK
U2 - 10.1111/j.1468-2494.2008.00441.x
DO - 10.1111/j.1468-2494.2008.00441.x
M3 - Article
C2 - 18452434
AN - SCOPUS:43049135504
SN - 0142-5463
VL - 30
SP - 175
EP - 182
JO - International Journal of Cosmetic Science
JF - International Journal of Cosmetic Science
IS - 3
ER -