Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy

Alexandre Dizeux; Thomas Payen; Guillaume Barrois; Capucine Baldini; Delphine Le Guillou Buffelo; Eva Comperat; Jean Luc Gennisson; Mickael Tanter; S. Lori Bridal

doi:10.1109/ULTSYM.2014.0281

Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy

Alexandre Dizeux, Thomas Payen, Guillaume Barrois, Capucine Baldini, Delphine Le Guillou Buffelo, Eva Comperat, Jean Luc Gennisson, Mickael Tanter, S. Lori Bridal

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Conference contribution › Revue par des pairs

1 Citation (Scopus)

Résumé

Robust, novel information on tumor microenvironment would improve therapeutic follow-up in oncology. Shear wave elastography (SWE) evaluates Young's modulus (stiffness) based on shear wave velocity. Dynamic contrast-enhanced ultrasound (DCE-US) traces microvascular flow with intravascular microbubbles. In this study, an ectopic tumor model was modified using two different types of drugs a cytotoxic (cyclophosphamide) and an anti-angiogenic (sunitinib). Both DCE-US and SWE imaging were sensitive to functional, physiological and mechanical modifications of the tumor and provided complementarity information to describe these modifications.

langue originale	Anglais
titre	IEEE International Ultrasonics Symposium, IUS
Editeur	IEEE Computer Society
Pages	1144-1147
Nombre de pages	4
ISBN (Electronique)	9781479970490
Les DOIs	https://doi.org/10.1109/ULTSYM.2014.0281
état	Publié - 20 oct. 2014
Modification externe	Oui
Evénement	2014 IEEE International Ultrasonics Symposium, IUS 2014 - Chicago, États-Unis Durée: 3 sept. 2014 → 6 sept. 2014

Série de publications

Nom	IEEE International Ultrasonics Symposium, IUS
ISSN (imprimé)	1948-5719
ISSN (Electronique)	1948-5727

Une conférence

Une conférence	2014 IEEE International Ultrasonics Symposium, IUS 2014
Pays/Territoire	États-Unis
La ville	Chicago
période	3/09/14 → 6/09/14

Accès au document

10.1109/ULTSYM.2014.0281

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Lien vers la publication dans Scopus

Contient cette citation

Dizeux, A., Payen, T., Barrois, G., Baldini, C., Le Guillou Buffelo, D., Comperat, E., Gennisson, J. L., Tanter, M., & Bridal, S. L. (2014). Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy. Dans IEEE International Ultrasonics Symposium, IUS (p. 1144-1147). Article 6931972 (IEEE International Ultrasonics Symposium, IUS). IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2014.0281

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title = "Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy",

abstract = "Robust, novel information on tumor microenvironment would improve therapeutic follow-up in oncology. Shear wave elastography (SWE) evaluates Young's modulus (stiffness) based on shear wave velocity. Dynamic contrast-enhanced ultrasound (DCE-US) traces microvascular flow with intravascular microbubbles. In this study, an ectopic tumor model was modified using two different types of drugs a cytotoxic (cyclophosphamide) and an anti-angiogenic (sunitinib). Both DCE-US and SWE imaging were sensitive to functional, physiological and mechanical modifications of the tumor and provided complementarity information to describe these modifications.",

keywords = "angiogenesis, dynamic contrast-enhanced ultrasound, fibrosis, functional vascular network, necrosis, shear wave elastography, stiffness, tumor microenvironment",

author = "Alexandre Dizeux and Thomas Payen and Guillaume Barrois and Capucine Baldini and {Le Guillou Buffelo}, Delphine and Eva Comperat and Gennisson, {Jean Luc} and Mickael Tanter and Bridal, {S. Lori}",

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year = "2014",

month = oct,

day = "20",

doi = "10.1109/ULTSYM.2014.0281",

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series = "IEEE International Ultrasonics Symposium, IUS",

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Dizeux, A, Payen, T, Barrois, G, Baldini, C, Le Guillou Buffelo, D, Comperat, E, Gennisson, JL, Tanter, M & Bridal, SL 2014, Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy. Dans IEEE International Ultrasonics Symposium, IUS., 6931972, IEEE International Ultrasonics Symposium, IUS, IEEE Computer Society, p. 1144-1147, 2014 IEEE International Ultrasonics Symposium, IUS 2014, Chicago, États-Unis, 3/09/14. https://doi.org/10.1109/ULTSYM.2014.0281

Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy. / Dizeux, Alexandre; Payen, Thomas; Barrois, Guillaume et al.
IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society, 2014. p. 1144-1147 6931972 (IEEE International Ultrasonics Symposium, IUS).

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Conference contribution › Revue par des pairs

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T1 - Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy

AU - Dizeux, Alexandre

AU - Payen, Thomas

AU - Barrois, Guillaume

AU - Baldini, Capucine

AU - Le Guillou Buffelo, Delphine

AU - Comperat, Eva

AU - Gennisson, Jean Luc

AU - Tanter, Mickael

AU - Bridal, S. Lori

PY - 2014/10/20

Y1 - 2014/10/20

N2 - Robust, novel information on tumor microenvironment would improve therapeutic follow-up in oncology. Shear wave elastography (SWE) evaluates Young's modulus (stiffness) based on shear wave velocity. Dynamic contrast-enhanced ultrasound (DCE-US) traces microvascular flow with intravascular microbubbles. In this study, an ectopic tumor model was modified using two different types of drugs a cytotoxic (cyclophosphamide) and an anti-angiogenic (sunitinib). Both DCE-US and SWE imaging were sensitive to functional, physiological and mechanical modifications of the tumor and provided complementarity information to describe these modifications.

AB - Robust, novel information on tumor microenvironment would improve therapeutic follow-up in oncology. Shear wave elastography (SWE) evaluates Young's modulus (stiffness) based on shear wave velocity. Dynamic contrast-enhanced ultrasound (DCE-US) traces microvascular flow with intravascular microbubbles. In this study, an ectopic tumor model was modified using two different types of drugs a cytotoxic (cyclophosphamide) and an anti-angiogenic (sunitinib). Both DCE-US and SWE imaging were sensitive to functional, physiological and mechanical modifications of the tumor and provided complementarity information to describe these modifications.

KW - angiogenesis

KW - dynamic contrast-enhanced ultrasound

KW - fibrosis

KW - functional vascular network

KW - necrosis

KW - shear wave elastography

KW - stiffness

KW - tumor microenvironment

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Dizeux A, Payen T, Barrois G, Baldini C, Le Guillou Buffelo D, Comperat E et al. Complementarity of shear wave elastography and dynamic contrast-enhanced ultrasound to discriminate tumor modifications during antiangiogenic and cytotoxic therapy. Dans IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society. 2014. p. 1144-1147. 6931972. (IEEE International Ultrasonics Symposium, IUS). doi: 10.1109/ULTSYM.2014.0281