Résumé
There is little information in the medical literature about skin rashes associated with dactinomycin in the absence of radiotherapy. We report a 12-month-old male child who developed a severe cutaneous reaction that consisted of a widespread pruritic papular eruption associated with fever and a poor general state after dactinomycin administration. Skin biopsy specimen findings confirmed the diagnosis of lichenoid eruption. The rash improved with topical steroid treatment and completely resolved within 1 month with persistence of a residual mild hyperpigmentation. Dactinomycin administration was discontinued for the remaining cycles of chemotherapy.
langue originale | Anglais |
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Pages (de - à) | 503-506 |
Nombre de pages | 4 |
journal | Pediatric Dermatology |
Volume | 23 |
Numéro de publication | 5 |
Les DOIs | |
état | Publié - 1 sept. 2006 |