Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication

D. Pekin; C. Normand; S. Kotsopoulos; X. Li; L. Benhaim; O. Bouché; T. Lecompte; D. Le Corre; T. Hor; Z. El Harrak; P. Nizard; D. Link; J. B. Hutschinson; P. Laurent-Puig; V. Taly

Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication

D. Pekin, C. Normand, S. Kotsopoulos, X. Li, L. Benhaim, O. Bouché, T. Lecompte, D. Le Corre, T. Hor, Z. El Harrak, P. Nizard, D. Link, J. B. Hutschinson, P. Laurent-Puig, V. Taly

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Conference contribution › Revue par des pairs

Résumé

We used a multiplex droplet-based digital PCR method in a retrospective study including 181 patients with a metastatic colorectal cancer (mCRC) for the quantitative and sensitive detection of KRAS and BRAF mutations in DNA extracted from tumors.

langue originale	Anglais
titre	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Editeur	Chemical and Biological Microsystems Society
Pages	1806-1808
Nombre de pages	3
ISBN (imprimé)	9781632666246
état	Publié - 1 janv. 2013
Modification externe	Oui
Evénement	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Allemagne Durée: 27 oct. 2013 → 31 oct. 2013

Série de publications

Nom	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume	3

Une conférence

Une conférence	17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Pays/Territoire	Allemagne
La ville	Freiburg
période	27/10/13 → 31/10/13

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Contient cette citation

Pekin, D., Normand, C., Kotsopoulos, S., Li, X., Benhaim, L., Bouché, O., Lecompte, T., Le Corre, D., Hor, T., El Harrak, Z., Nizard, P., Link, D., Hutschinson, J. B., Laurent-Puig, P., & Taly, V. (2013). Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication. Dans 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 (p. 1806-1808). (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Vol 3). Chemical and Biological Microsystems Society.

Pekin, D. ; Normand, C. ; Kotsopoulos, S. et al. / Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics : Clinical implication. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society, 2013. p. 1806-1808 (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013).

@inproceedings{e2dc37548dd6453187d561b5521bcd91,

title = "Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication",

abstract = "We used a multiplex droplet-based digital PCR method in a retrospective study including 181 patients with a metastatic colorectal cancer (mCRC) for the quantitative and sensitive detection of KRAS and BRAF mutations in DNA extracted from tumors.",

keywords = "Cancer biomarkers, Digital PCR (dPCR), Droplet-based microfluidics, KRAS mutations",

author = "D. Pekin and C. Normand and S. Kotsopoulos and X. Li and L. Benhaim and O. Bouch{\'e} and T. Lecompte and {Le Corre}, D. and T. Hor and {El Harrak}, Z. and P. Nizard and D. Link and Hutschinson, {J. B.} and P. Laurent-Puig and V. Taly",

year = "2013",

month = jan,

day = "1",

language = "English",

isbn = "9781632666246",

series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",

publisher = "Chemical and Biological Microsystems Society",

pages = "1806--1808",

booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",

note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",

}

Pekin, D, Normand, C, Kotsopoulos, S, Li, X, Benhaim, L, Bouché, O, Lecompte, T, Le Corre, D, Hor, T, El Harrak, Z, Nizard, P, Link, D, Hutschinson, JB, Laurent-Puig, P & Taly, V 2013, Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication. Dans 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, VOL. 3, Chemical and Biological Microsystems Society, p. 1806-1808, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013, Freiburg, Allemagne, 27/10/13.

Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication. / Pekin, D.; Normand, C.; Kotsopoulos, S. et al.
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society, 2013. p. 1806-1808 (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Vol 3).

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Conference contribution › Revue par des pairs

TY - GEN

T1 - Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics

T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013

AU - Pekin, D.

AU - Normand, C.

AU - Kotsopoulos, S.

AU - Li, X.

AU - Benhaim, L.

AU - Bouché, O.

AU - Lecompte, T.

AU - Le Corre, D.

AU - Hor, T.

AU - El Harrak, Z.

AU - Nizard, P.

AU - Link, D.

AU - Hutschinson, J. B.

AU - Laurent-Puig, P.

AU - Taly, V.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - We used a multiplex droplet-based digital PCR method in a retrospective study including 181 patients with a metastatic colorectal cancer (mCRC) for the quantitative and sensitive detection of KRAS and BRAF mutations in DNA extracted from tumors.

AB - We used a multiplex droplet-based digital PCR method in a retrospective study including 181 patients with a metastatic colorectal cancer (mCRC) for the quantitative and sensitive detection of KRAS and BRAF mutations in DNA extracted from tumors.

KW - Cancer biomarkers

KW - Digital PCR (dPCR)

KW - Droplet-based microfluidics

KW - KRAS mutations

UR - http://www.scopus.com/inward/record.url?scp=84907372240&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84907372240

SN - 9781632666246

T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013

SP - 1806

EP - 1808

BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013

PB - Chemical and Biological Microsystems Society

Y2 - 27 October 2013 through 31 October 2013

ER -

Pekin D, Normand C, Kotsopoulos S, Li X, Benhaim L, Bouché O et al. Detection and quantification of minority KRAS subclones in tumors using droplet-based microfluidics: Clinical implication. Dans 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society. 2013. p. 1806-1808. (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013).