TY - JOUR
T1 - Disseminated and circulating tumor cells in gastrointestinal oncology
AU - Bidard, F. C.
AU - Ferrand, F. R.
AU - Huguet, F.
AU - Hammel, P.
AU - Louvet, C.
AU - Malka, D.
AU - Boige, V.
AU - Ducreux, M.
AU - Andre, T.
AU - de Gramont, A.
AU - Mariani, P.
AU - Pierga, J. Y.
PY - 2012/5/1
Y1 - 2012/5/1
N2 - Circulating (CTCs) and disseminated tumor cells (DTCs) are two different steps in the metastatic process. Several recent techniques have allowed detection of these cells in patients, and have generated many results using different isolation techniques in small cohorts. Herein, we review the detection results and their clinical consequence in esophageal, gastric, pancreatic, colorectal, and liver carcinomas, and discuss their possible applications as new biomarkers.
AB - Circulating (CTCs) and disseminated tumor cells (DTCs) are two different steps in the metastatic process. Several recent techniques have allowed detection of these cells in patients, and have generated many results using different isolation techniques in small cohorts. Herein, we review the detection results and their clinical consequence in esophageal, gastric, pancreatic, colorectal, and liver carcinomas, and discuss their possible applications as new biomarkers.
KW - Biomarker
KW - Circulating tumor cells
KW - Disseminated tumor cells
KW - Gastrointestinal cancer
KW - Micrometastasis
UR - http://www.scopus.com/inward/record.url?scp=84859420898&partnerID=8YFLogxK
U2 - 10.1016/j.critrevonc.2011.05.008
DO - 10.1016/j.critrevonc.2011.05.008
M3 - Review article
C2 - 21680197
AN - SCOPUS:84859420898
SN - 1040-8428
VL - 82
SP - 103
EP - 115
JO - Critical Reviews in Oncology/Hematology
JF - Critical Reviews in Oncology/Hematology
IS - 2
ER -