Résumé
The new developments of chemotherapy in colorectal cancer have shown that it was possible with new drugs to increase response rate and survival of the patients. It has been shown that it was possible to treat some patients with surgery after response to therapy. Considering this aim of treatment it seems important to increase more and more the response rate to chemotherapy. This seems possible with new schedules of chemotherapy. With irinotecan based regimens, there are two ways to intensify the treatment. The first one is to increase the doses of irinotecan combined with 5FU, and the other one is to combine the three major agents of chemotherapy of colorectal cancer leading to the concept of three therapy. These news approaches give high response rate up to 75 % and in 95 to 100 % of tumour growth control.
| Titre traduit de la contribution | Chimiothérapie du cancer colorectal et intensification |
|---|---|
| langue originale | Anglais |
| Pages (de - à) | 683-689 |
| Nombre de pages | 7 |
| journal | Acta Endoscopica |
| Volume | 32 |
| Numéro de publication | 4 |
| Les DOIs | |
| état | Publié - 1 janv. 2002 |