TY - JOUR
T1 - Epidemiology of head and neck cancers
T2 - An update
AU - Aupérin, Anne
N1 - Publisher Copyright:
© 2020 Lippincott Williams and Wilkins. All rights reserved.
PY - 2020/5/1
Y1 - 2020/5/1
N2 - Purpose of reviewThis review attempts to give an update of epidemiological knowledge on head and neck cancers (HNC).Recent findingsWorldwide, from 1990 to 2017, incidence rates for larynx and nasopharyngeal cancers decreased, whereas they increased for oro/hypopharyngeal cancers and lip/oral cavity cancers. They are still markedly higher among men than women. South Asia has the highest HNC incidence rate, followed by Europe, North America, and Australasia.Tobacco and alcohol remain the major risk factors. Rate of cancers attributable to human papillomavirus (HPV) among HNCs is highly depending on world region and tobacco use prevalence. It increases in high-income countries. In the US population, the number of HPV-attributable oropharyngeal cancers now exceeds the number of cervix cancers. HPV vaccination for boys is recommended in an increasing number of countries. Many occupations are associated with an increased HNC risk. Fruits and vegetables intake have a protective effect against HNC.SummaryTo decrease HNC incidence, measures to reduce tobacco use and alcohol consumption remain essential. Improvement of HPV vaccination coverage is also a major objective. Reduction of carcinogens at occupation, protection of workers from carcinogen exposures, education for better diet, and easy and affordable access to fruits and vegetables can contribute to incidence decrease.
AB - Purpose of reviewThis review attempts to give an update of epidemiological knowledge on head and neck cancers (HNC).Recent findingsWorldwide, from 1990 to 2017, incidence rates for larynx and nasopharyngeal cancers decreased, whereas they increased for oro/hypopharyngeal cancers and lip/oral cavity cancers. They are still markedly higher among men than women. South Asia has the highest HNC incidence rate, followed by Europe, North America, and Australasia.Tobacco and alcohol remain the major risk factors. Rate of cancers attributable to human papillomavirus (HPV) among HNCs is highly depending on world region and tobacco use prevalence. It increases in high-income countries. In the US population, the number of HPV-attributable oropharyngeal cancers now exceeds the number of cervix cancers. HPV vaccination for boys is recommended in an increasing number of countries. Many occupations are associated with an increased HNC risk. Fruits and vegetables intake have a protective effect against HNC.SummaryTo decrease HNC incidence, measures to reduce tobacco use and alcohol consumption remain essential. Improvement of HPV vaccination coverage is also a major objective. Reduction of carcinogens at occupation, protection of workers from carcinogen exposures, education for better diet, and easy and affordable access to fruits and vegetables can contribute to incidence decrease.
KW - alcohol
KW - diet
KW - head and neck cancers
KW - human papilloma virus vaccination
KW - occupations
KW - tobacco
UR - http://www.scopus.com/inward/record.url?scp=85083041981&partnerID=8YFLogxK
U2 - 10.1097/CCO.0000000000000629
DO - 10.1097/CCO.0000000000000629
M3 - Review article
C2 - 32209823
AN - SCOPUS:85083041981
SN - 1040-8746
VL - 32
SP - 178
EP - 186
JO - Current Opinion in Oncology
JF - Current Opinion in Oncology
IS - 3
ER -