Epstein-Barr virus: Exploiting the immune system by interfering with defective ribosomal products

Sébastien Apcher; Robin Fahraeus; Bénédicte Manoury

doi:10.1016/j.micinf.2004.08.003

Epstein-Barr virus: Exploiting the immune system by interfering with defective ribosomal products

Sébastien Apcher, Robin Fahraeus, Bénédicte Manoury

Résultats de recherche: Contribution à un journal › Brève enquête › Revue par des pairs

8 Citations (Scopus)

Résumé

The interaction of cytotoxic T lymphocytes with major histocompatibility complex (MHC)-peptide complexes is a critical step toward the initiation and propagation of specific immune responses against viral infection. Here we review new evidence, taking Epstein-Barr virus as an example, showing that defective ribosomal products provide an important supply of endogenous peptides for entry into the MHC class I antigen-presentation pathway.

langue originale	Anglais
Pages (de - à)	1212-1218
Nombre de pages	7
journal	Microbes and Infection
Volume	6
Numéro de publication	13
Les DOIs	https://doi.org/10.1016/j.micinf.2004.08.003
état	Publié - 1 janv. 2004
Modification externe	Oui

Accès au document

10.1016/j.micinf.2004.08.003

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Contient cette citation

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abstract = "The interaction of cytotoxic T lymphocytes with major histocompatibility complex (MHC)-peptide complexes is a critical step toward the initiation and propagation of specific immune responses against viral infection. Here we review new evidence, taking Epstein-Barr virus as an example, showing that defective ribosomal products provide an important supply of endogenous peptides for entry into the MHC class I antigen-presentation pathway.",

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