Etude de la distribution des antigènes HLA dans une population et comparaison de deux populations.

F. de Vathaire; C. Hill; M. Lipinski; C. Parmentier; R. Flamant

Etude de la distribution des antigènes HLA dans une population et comparaison de deux populations.

F. de Vathaire, C. Hill, M. Lipinski, C. Parmentier, R. Flamant

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Résumé

HLA complex is made up of numerous loci whose alleles are codominant. Several associations between HLA antigens and diseases have been identified. Analysis of these associations require statistical methods taking into account the number of tests and the existence of alleles which have not yet been identified. Statistical methods for the estimation and the comparison of alleles frequencies are presented for genotypic, phenotypic and marginal data. An example concerning patients with medullary thyroid carcinoma illustrates these methods.

Titre traduit de la contribution	Study of the distribution of HLA antigens within a population and a comparison between 2 populations
langue originale	Français
Pages (de - à)	1-9
Nombre de pages	9
journal	Revue d'Epidemiologie et de Sante Publique
Volume	34
Numéro de publication	1
état	Publié - 1 janv. 1986

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Contient cette citation

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title = "Etude de la distribution des antig{\`e}nes HLA dans une population et comparaison de deux populations.",

abstract = "HLA complex is made up of numerous loci whose alleles are codominant. Several associations between HLA antigens and diseases have been identified. Analysis of these associations require statistical methods taking into account the number of tests and the existence of alleles which have not yet been identified. Statistical methods for the estimation and the comparison of alleles frequencies are presented for genotypic, phenotypic and marginal data. An example concerning patients with medullary thyroid carcinoma illustrates these methods.",

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AU - Parmentier, C.

AU - Flamant, R.

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AB - HLA complex is made up of numerous loci whose alleles are codominant. Several associations between HLA antigens and diseases have been identified. Analysis of these associations require statistical methods taking into account the number of tests and the existence of alleles which have not yet been identified. Statistical methods for the estimation and the comparison of alleles frequencies are presented for genotypic, phenotypic and marginal data. An example concerning patients with medullary thyroid carcinoma illustrates these methods.

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