Résumé
The analysis by stopped-flow of the interaction of fluorescent agonist (C5DACho1) with the acetylcholine receptor in its membrane-bound form reveals several kinetic steps: a fast one, in the millisecond range, associated with the binding of C5DACho1 to a high affinity state and a "medium" and "slow" one, the last one representing possibly an isomerisation of the receptor molecule towards the high affinity state.
Titre traduit de la contribution | Study by a rapid mixing method of the interaction between a fluorescent cholinergic agonist and membrane fragments rich in cholinergic receptors from Torpedo marmorata |
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langue originale | Français |
Pages (de - à) | 771-774 |
Nombre de pages | 4 |
journal | Comptes rendus hebdomadaires des seances de l"Academie des sciences. Serie D: Sciences naturelles |
Volume | 284 |
Numéro de publication | 9 |
état | Publié - 28 févr. 1977 |