TY - JOUR
T1 - ETV6 gene rearrangements in invasive breast carcinoma
AU - Letessier, Anne
AU - Ginestier, Christophe
AU - Charafe-Jauffret, Emmanuelle
AU - Cervera, Nathalie
AU - Adélaïde, José
AU - Gelsi-Boyer, Véronique
AU - Ahomadegbe, Jean Charles
AU - Benard, Jean
AU - Jacquemier, Jocelyne
AU - Birnbaum, Daniel
AU - Chaffanet, Max
PY - 2005/9/1
Y1 - 2005/9/1
N2 - The ETV6/TEL gene encodes a transcription factor frequently rearranged in several types of cancer. We looked for ETV6 rearrangements in invasive breast cancer using fluorescence in situ hybridization (FISH) of BAC probes on sections of tissue microarrays containing 632 tumor samples. Of these samples, signal of sufficient quality for screening by FISH was obtained for 356. Five cases (one lobular, one nontypical secretory, one mixed, and two ductal carcinomas) showed ETV6 rearrangement.
AB - The ETV6/TEL gene encodes a transcription factor frequently rearranged in several types of cancer. We looked for ETV6 rearrangements in invasive breast cancer using fluorescence in situ hybridization (FISH) of BAC probes on sections of tissue microarrays containing 632 tumor samples. Of these samples, signal of sufficient quality for screening by FISH was obtained for 356. Five cases (one lobular, one nontypical secretory, one mixed, and two ductal carcinomas) showed ETV6 rearrangement.
UR - http://www.scopus.com/inward/record.url?scp=23044490102&partnerID=8YFLogxK
U2 - 10.1002/gcc.20200
DO - 10.1002/gcc.20200
M3 - Article
C2 - 15887243
AN - SCOPUS:23044490102
SN - 1045-2257
VL - 44
SP - 103
EP - 108
JO - Genes Chromosomes and Cancer
JF - Genes Chromosomes and Cancer
IS - 1
ER -