European collaboration in trials of new agents for children with cancer

S. Ablett, F. Doz, B. Morland, G. Vassal

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    11 Citations (Scopus)

    Résumé

    Childhood cancer is a relatively rare disease, representing just 1% of all malignancies. Within Europe, this represents some 12,000 new cases each year, with approximately 1600 a year in the United Kingdom and 1800 in France. International collaboration in phase III trials of childhood cancer has been the norm for many years, traditionally within Europe, but, largely because of organisational considerations, phase I and II trials have only been conducted on a national basis. With overall cure rates in the region of 70%, relatively few children are available for these early drug trials. Access to new drugs is also a major problem. Against this background, a United Kingdom (UK)/French 'new agent' collaboration was established, expanding subsequently into a wider European grouping. This paper documents the history of that collaboration, the outcomes and future challenges.

    langue originaleAnglais
    Pages (de - à)1886-1892
    Nombre de pages7
    journalEuropean Journal of Cancer
    Volume40
    Numéro de publication12
    Les DOIs
    étatPublié - 1 janv. 2004

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