Facilitating a culture of responsible and effective sharing of cancer genome data

Lillian L. Siu; Mark Lawler; David Haussler; Bartha Maria Knoppers; Jeremy Lewin; Daniel J. Vis; Rachel G. Liao; Fabrice Andre; Ian Banks; J. Carl Barrett; Carlos Caldas; Anamaria Aranha Camargo; Rebecca C. Fitzgerald; Mao Mao; John E. Mattison; William Pao; William R. Sellers; Patrick Sullivan; Bin Tean Teh; Robyn L. Ward; Jean Claude ZenKlusen; Charles L. Sawyers; Emile E. Voest

doi:10.1038/nm.4089

Facilitating a culture of responsible and effective sharing of cancer genome data

Lillian L. Siu, Mark Lawler, David Haussler, Bartha Maria Knoppers, Jeremy Lewin, Daniel J. Vis, Rachel G. Liao, Fabrice Andre, Ian Banks, J. Carl Barrett, Carlos Caldas, Anamaria Aranha Camargo, Rebecca C. Fitzgerald, Mao Mao, John E. Mattison, William Pao, William R. Sellers, Patrick Sullivan, Bin Tean Teh, Robyn L. WardJean Claude ZenKlusen, Charles L. Sawyers, Emile E. Voest

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Chapter › Revue par des pairs

Résumé

Rapid and affordable tumor molecular profiling has led to an explosion of clinical and genomic data poised to enhance the diagnosis, prognostication and treatment of cancer. A critical point has now been reached at which the analysis and storage of annotated clinical and genomic information in unconnected silos will stall the advancement of precision cancer care. Information systems must be harmonized to overcome the multiple technical and logistical barriers to data sharing. Against this backdrop, the Global Alliance for Genomic Health (GA4GH) was established in 2013 to create a common framework that enables responsible, voluntary and secure sharing of clinical and genomic data. This Perspective from the GA4GH Clinical Working Group Cancer Task Team highlights the data-aggregation challenges faced by the field, suggests potential collaborative solutions and describes how GA4GH can catalyze a harmonized data-sharing culture.

langue originale	Anglais
titre	Getting to Good
Sous-titre	Research Integrity in the Biomedical Sciences
Editeur	Springer International Publishing
Pages	539-548
Nombre de pages	10
ISBN (Electronique)	9783319513584
ISBN (imprimé)	9783319513577
Les DOIs	https://doi.org/10.1038/nm.4089
état	Publié - 23 juil. 2018
Modification externe	Oui

Accès au document

10.1038/nm.4089

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Contient cette citation

Siu, L. L., Lawler, M., Haussler, D., Knoppers, B. M., Lewin, J., Vis, D. J., Liao, R. G., Andre, F., Banks, I., Barrett, J. C., Caldas, C., Camargo, A. A., Fitzgerald, R. C., Mao, M., Mattison, J. E., Pao, W., Sellers, W. R., Sullivan, P., Teh, B. T., ... Voest, E. E. (2018). Facilitating a culture of responsible and effective sharing of cancer genome data. Dans Getting to Good: Research Integrity in the Biomedical Sciences (p. 539-548). Springer International Publishing. https://doi.org/10.1038/nm.4089

@inbook{b97e26e9c8454c51bc216188b303b34e,

title = "Facilitating a culture of responsible and effective sharing of cancer genome data",

abstract = "Rapid and affordable tumor molecular profiling has led to an explosion of clinical and genomic data poised to enhance the diagnosis, prognostication and treatment of cancer. A critical point has now been reached at which the analysis and storage of annotated clinical and genomic information in unconnected silos will stall the advancement of precision cancer care. Information systems must be harmonized to overcome the multiple technical and logistical barriers to data sharing. Against this backdrop, the Global Alliance for Genomic Health (GA4GH) was established in 2013 to create a common framework that enables responsible, voluntary and secure sharing of clinical and genomic data. This Perspective from the GA4GH Clinical Working Group Cancer Task Team highlights the data-aggregation challenges faced by the field, suggests potential collaborative solutions and describes how GA4GH can catalyze a harmonized data-sharing culture.",

author = "Siu, {Lillian L.} and Mark Lawler and David Haussler and Knoppers, {Bartha Maria} and Jeremy Lewin and Vis, {Daniel J.} and Liao, {Rachel G.} and Fabrice Andre and Ian Banks and Barrett, {J. Carl} and Carlos Caldas and Camargo, {Anamaria Aranha} and Fitzgerald, {Rebecca C.} and Mao Mao and Mattison, {John E.} and William Pao and Sellers, {William R.} and Patrick Sullivan and Teh, {Bin Tean} and Ward, {Robyn L.} and ZenKlusen, {Jean Claude} and Sawyers, {Charles L.} and Voest, {Emile E.}",

note = "Publisher Copyright: {\textcopyright} 2016, Nature Medicine.",

year = "2018",

month = jul,

day = "23",

doi = "10.1038/nm.4089",

language = "English",

isbn = "9783319513577",

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booktitle = "Getting to Good",

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Siu, LL, Lawler, M, Haussler, D, Knoppers, BM, Lewin, J, Vis, DJ, Liao, RG, Andre, F, Banks, I, Barrett, JC, Caldas, C, Camargo, AA, Fitzgerald, RC, Mao, M, Mattison, JE, Pao, W, Sellers, WR, Sullivan, P, Teh, BT, Ward, RL, ZenKlusen, JC, Sawyers, CL & Voest, EE 2018, Facilitating a culture of responsible and effective sharing of cancer genome data. Dans Getting to Good: Research Integrity in the Biomedical Sciences. Springer International Publishing, p. 539-548. https://doi.org/10.1038/nm.4089

Facilitating a culture of responsible and effective sharing of cancer genome data. / Siu, Lillian L.; Lawler, Mark; Haussler, David et al.
Getting to Good: Research Integrity in the Biomedical Sciences. Springer International Publishing, 2018. p. 539-548.

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Chapter › Revue par des pairs

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AU - Lewin, Jeremy

AU - Vis, Daniel J.

AU - Liao, Rachel G.

AU - Andre, Fabrice

AU - Banks, Ian

AU - Barrett, J. Carl

AU - Caldas, Carlos

AU - Camargo, Anamaria Aranha

AU - Fitzgerald, Rebecca C.

AU - Mao, Mao

AU - Mattison, John E.

AU - Pao, William

AU - Sellers, William R.

AU - Sullivan, Patrick

AU - Teh, Bin Tean

AU - Ward, Robyn L.

AU - ZenKlusen, Jean Claude

AU - Sawyers, Charles L.

AU - Voest, Emile E.

PY - 2018/7/23

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AB - Rapid and affordable tumor molecular profiling has led to an explosion of clinical and genomic data poised to enhance the diagnosis, prognostication and treatment of cancer. A critical point has now been reached at which the analysis and storage of annotated clinical and genomic information in unconnected silos will stall the advancement of precision cancer care. Information systems must be harmonized to overcome the multiple technical and logistical barriers to data sharing. Against this backdrop, the Global Alliance for Genomic Health (GA4GH) was established in 2013 to create a common framework that enables responsible, voluntary and secure sharing of clinical and genomic data. This Perspective from the GA4GH Clinical Working Group Cancer Task Team highlights the data-aggregation challenges faced by the field, suggests potential collaborative solutions and describes how GA4GH can catalyze a harmonized data-sharing culture.

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