Facteurs pronostiques des métastases cérébrales

Romuald Le Scodan, Christophe Massard, Georges Noël

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    5 Citations (Scopus)

    Résumé

    Approximately 20 to 40 % of patients with metastatic cancer will develop brain metastases (BM) during the disease course. Whole-brain radiation therapy (WBRT) is considered the standard treatment for most patients, particularly those with extensive intracranial disease, providing symptom relief and increasing median and overall survival. Despite WBRT, the prognosis for the general population of patients with BM remains poor, with a median survival time of approximately five months. Several studies have examined the relative contribution of patient characteristics to survival and have attempted to identify subgroups of patients with substantially different outcomes in order to tailor therapy and to influence the design, stratification and interpretation of future clinical trials. Here, we review the main prognostic factors and prognostic scores in patients with BM and the value and limits of these prognostic scores in clinical practice.

    Titre traduit de la contributionPrognostic factors for patients with brain metastases
    langue originaleFrançais
    Pages (de - à)45-50
    Nombre de pages6
    journalBulletin du Cancer
    Volume100
    Numéro de publication1
    Les DOIs
    étatPublié - 1 janv. 2013

    mots-clés

    • Brain metastases
    • Prognostic scores

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