TY - JOUR
T1 - Ghrelin and leptin regulating wound healing
AU - Kroemer, Guido
AU - Zitvogel, Laurence
N1 - Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/10/1
Y1 - 2022/10/1
N2 - A recent article by Kratofil et al. investigated the immune inflammatory response against Staphylococcus aureus-contaminated foreign bodies placed under mouse skin. In this model, neutrophils are indispensable for bacterial clearance, while monocyte-derived macrophages are required for optimal wound healing. Intriguingly, ghrelin produced by macrophages favors, and leptin produced by hypodermal adipocytes inhibits, an adequate foreign body response.
AB - A recent article by Kratofil et al. investigated the immune inflammatory response against Staphylococcus aureus-contaminated foreign bodies placed under mouse skin. In this model, neutrophils are indispensable for bacterial clearance, while monocyte-derived macrophages are required for optimal wound healing. Intriguingly, ghrelin produced by macrophages favors, and leptin produced by hypodermal adipocytes inhibits, an adequate foreign body response.
UR - http://www.scopus.com/inward/record.url?scp=85136605875&partnerID=8YFLogxK
U2 - 10.1016/j.it.2022.08.005
DO - 10.1016/j.it.2022.08.005
M3 - Short survey
C2 - 36028447
AN - SCOPUS:85136605875
SN - 1471-4906
VL - 43
SP - 777
EP - 779
JO - Trends in Immunology
JF - Trends in Immunology
IS - 10
ER -