Imaging of melanoma: Usefulness of ultrasonography before and after contrast injection for diagnosis and early evaluation of treatment

Linda Chami, Nathalie Lassau, Mohamed Chebil, Caroline Robert

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    26 Citations (Scopus)

    Résumé

    High-frequency ultrasound (8-14 MHz) is routinely used to display cutaneous melanomas. Maximum thickness measurement (Breslow index) has been shown to be well correlated to histologic findings for lesions of more than 0.75 mm. Some morphological criteria (strong delineation, hypoechoic texture, homogeneity) have been reported to help differentiate between malignant and benign pigmented blue lesions, but remain insufficient. Vascular ultrasound analysis using Doppler mode provides additional information and showed good specificity for malignancy (90%-100%), but variable sensitivity (34%-100%). Recent advances in ultrasound imaging allow functional evaluation. Likewise, dynamic contrastenhanced ultrasound using contrast medium injection and specific perfusion and quantification software showed promising results in clinical and preclinical trials for early prediction of tumor response to target treatments.

    langue originaleAnglais
    Pages (de - à)1-6
    Nombre de pages6
    journalClinical, Cosmetic and Investigational Dermatology
    Volume4
    Les DOIs
    étatPublié - 1 janv. 2011

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