Résumé
Autologous T cells engineered to express a chimeric antigen receptor (CAR) remain poorly effective against solid tumors, partly because solid neoplasms can establish an immunosuppressive microenvironment. Recent findings by Srivastava et al. suggest that immunogenic chemotherapeutics such as oxaliplatin can be harnessed to maximize the capacity of CAR T cells to infiltrate and control solid tumors.
langue originale | Anglais |
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Pages (de - à) | 179-181 |
Nombre de pages | 3 |
journal | Trends in Cancer |
Volume | 7 |
Numéro de publication | 3 |
Les DOIs | |
état | Publié - 1 mars 2021 |