Immunotherapy of hpv-associated head and neck cancer Critical parameters

Mevyn Nizard, Federico Sandoval, Cecile Badoual, Helene Pere, Magali Terme, Stephane Hans, Nadine Benhamouda, Clemence Granier, Daniel Brasnu, Eric Tartour

Résultats de recherche: Contribution à un journalArticleRevue par des pairs

13 Citations (Scopus)

Résumé

Various arguments support the development of a vaccine targeting human papillomavirus (HPV) for the treatment of HPV-associated head and neck cancer. However, the mucosal localization of this tumor, the HPV-driven downregulation of MHC Class I molecules and various other immunosuppressive mechanisms must be carefully considered to improve the clinical efficacy of such an immunotherapeutic strategy.

langue originaleAnglais
Numéro d'articlee24534
journalOncoImmunology
Volume2
Numéro de publication6
Les DOIs
étatPublié - 1 juin 2013
Modification externeOui

Contient cette citation