TY - JOUR
T1 - Impact de l'HPV (Human Papilloma Virus) dans les carcinomes autres que gynécologiques
AU - Badoual, C.
AU - Tartour, E.
AU - Roussel, H.
AU - Bats, A. S.
AU - Pavie, J.
AU - Pernot, S.
AU - Weiss, L.
AU - Si Mohamed, A.
AU - Thariat, J.
AU - Hoffmann, C.
AU - Péré, H.
N1 - Publisher Copyright:
© 2015 Société nationale française de médecine interne (SNFMI).
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Worldwide, approximately 5 to 10% of the population is infected by a Human Papilloma Virus (HPV). Some of these viruses, with a high oncogenic risk (HPV HR), are responsible for about 5% of cancer. It is now accepted that almost all carcinomas of the cervix and the vulva are due to an HPV HR (HPV16 and 18) infection. However, these viruses are known to be involved in the carcinogenesis of many other cancers (head and neck [SCCHN], penis, anus). For head and neck cancer, HPV infection is considered as a good prognostic factor. The role of HPV HR in anal cancer is also extensively studied in high-risk patient's population. The role of HPV infection in the carcinogenesis of esophageal, bladder, lung, breast or skin cancers is still debated. Given the multiple possible locations of HPV HR infection, the question of optimizing the management of patients with a HPV+ cancer arises in the implementation of a comprehensive clinical and biological monitoring. It is the same in therapeutics with the existence of a preventive vaccination, for example.
AB - Worldwide, approximately 5 to 10% of the population is infected by a Human Papilloma Virus (HPV). Some of these viruses, with a high oncogenic risk (HPV HR), are responsible for about 5% of cancer. It is now accepted that almost all carcinomas of the cervix and the vulva are due to an HPV HR (HPV16 and 18) infection. However, these viruses are known to be involved in the carcinogenesis of many other cancers (head and neck [SCCHN], penis, anus). For head and neck cancer, HPV infection is considered as a good prognostic factor. The role of HPV HR in anal cancer is also extensively studied in high-risk patient's population. The role of HPV infection in the carcinogenesis of esophageal, bladder, lung, breast or skin cancers is still debated. Given the multiple possible locations of HPV HR infection, the question of optimizing the management of patients with a HPV+ cancer arises in the implementation of a comprehensive clinical and biological monitoring. It is the same in therapeutics with the existence of a preventive vaccination, for example.
KW - Cancer, Head and neck, Anus
KW - HPV (human papilloma virus)
UR - http://www.scopus.com/inward/record.url?scp=84937738718&partnerID=8YFLogxK
U2 - 10.1016/j.revmed.2015.01.003
DO - 10.1016/j.revmed.2015.01.003
M3 - Brève enquête
C2 - 25661671
AN - SCOPUS:84937738718
SN - 0248-8663
VL - 36
SP - 540
EP - 547
JO - Revue de Medecine Interne
JF - Revue de Medecine Interne
IS - 8
ER -