Impact of epidural analgesia on survival in patients undergoing complete cytoreductive surgery for ovarian cancer

Perrine Capmas; Valérie Billard; Sebastien Gouy; Catherine Lhommé; Patricia Pautier; Philippe Morice; Catherine Uzan

Impact of epidural analgesia on survival in patients undergoing complete cytoreductive surgery for ovarian cancer

Perrine Capmas, Valérie Billard, Sebastien Gouy, Catherine Lhommé, Patricia Pautier, Philippe Morice, Catherine Uzan

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

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Résumé

Background: Potential benefits of regional analgesia in reduction of cancer recurrence have been reported for breast and prostate cancer. The aim of this study was to evaluate the influence of regional analgesia on recurrence-free survival and overall survival in patients with advanced-stage ovarian cancer (ASOC) following complete cytoreduction. Patients and Methods: This is a retrospective study of 104 patients who had undergone complete cytoreduction for ASOC between 01/2007 and 1212009: 51 with patient controlled epidural analgesia (PCEA) and 53 without PCEA. Results: No significant difference was found between the two groups in terms of overall survival,- while there was a trend in favour of PCEA for disease free survival. Conclusion: In our study, regional analgesia had no clear impact on cancer recurrence. More studies on this subject are warranted in order to determine the possible impact of regional analgesia on ASOC.

langue originale	Anglais
Pages (de - à)	1537-1542
Nombre de pages	6
journal	Anticancer Research
Volume	32
Numéro de publication	4
état	Publié - 1 avr. 2012

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title = "Impact of epidural analgesia on survival in patients undergoing complete cytoreductive surgery for ovarian cancer",

abstract = "Background: Potential benefits of regional analgesia in reduction of cancer recurrence have been reported for breast and prostate cancer. The aim of this study was to evaluate the influence of regional analgesia on recurrence-free survival and overall survival in patients with advanced-stage ovarian cancer (ASOC) following complete cytoreduction. Patients and Methods: This is a retrospective study of 104 patients who had undergone complete cytoreduction for ASOC between 01/2007 and 1212009: 51 with patient controlled epidural analgesia (PCEA) and 53 without PCEA. Results: No significant difference was found between the two groups in terms of overall survival,- while there was a trend in favour of PCEA for disease free survival. Conclusion: In our study, regional analgesia had no clear impact on cancer recurrence. More studies on this subject are warranted in order to determine the possible impact of regional analgesia on ASOC.",

keywords = "Cytoreductive surgery, Epidural analgesia, Ovarian cancer",

author = "Perrine Capmas and Val{\'e}rie Billard and Sebastien Gouy and Catherine Lhomm{\'e} and Patricia Pautier and Philippe Morice and Catherine Uzan",

year = "2012",

month = apr,

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language = "English",

volume = "32",

pages = "1537--1542",

journal = "Anticancer Research",

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TY - JOUR

T1 - Impact of epidural analgesia on survival in patients undergoing complete cytoreductive surgery for ovarian cancer

AU - Capmas, Perrine

AU - Billard, Valérie

AU - Gouy, Sebastien

AU - Lhommé, Catherine

AU - Pautier, Patricia

AU - Morice, Philippe

AU - Uzan, Catherine

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Background: Potential benefits of regional analgesia in reduction of cancer recurrence have been reported for breast and prostate cancer. The aim of this study was to evaluate the influence of regional analgesia on recurrence-free survival and overall survival in patients with advanced-stage ovarian cancer (ASOC) following complete cytoreduction. Patients and Methods: This is a retrospective study of 104 patients who had undergone complete cytoreduction for ASOC between 01/2007 and 1212009: 51 with patient controlled epidural analgesia (PCEA) and 53 without PCEA. Results: No significant difference was found between the two groups in terms of overall survival,- while there was a trend in favour of PCEA for disease free survival. Conclusion: In our study, regional analgesia had no clear impact on cancer recurrence. More studies on this subject are warranted in order to determine the possible impact of regional analgesia on ASOC.

AB - Background: Potential benefits of regional analgesia in reduction of cancer recurrence have been reported for breast and prostate cancer. The aim of this study was to evaluate the influence of regional analgesia on recurrence-free survival and overall survival in patients with advanced-stage ovarian cancer (ASOC) following complete cytoreduction. Patients and Methods: This is a retrospective study of 104 patients who had undergone complete cytoreduction for ASOC between 01/2007 and 1212009: 51 with patient controlled epidural analgesia (PCEA) and 53 without PCEA. Results: No significant difference was found between the two groups in terms of overall survival,- while there was a trend in favour of PCEA for disease free survival. Conclusion: In our study, regional analgesia had no clear impact on cancer recurrence. More studies on this subject are warranted in order to determine the possible impact of regional analgesia on ASOC.

KW - Cytoreductive surgery

KW - Epidural analgesia

KW - Ovarian cancer

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SN - 0250-7005

VL - 32

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JO - Anticancer Research

JF - Anticancer Research

IS - 4

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