Intérêt de l'inhibine comme marqueur tumoral dans les tumeurs de la granulosa. Mise au point à propos de six cas supplémentaires traités à l'institut Gustave-Roussy

Lappöhn et al showed that inhibin can be used as a marker of granulosa cell tumors (GCT). Inhibin is a glycoprotein specifically produced by ovarian granulosa cells. This peptide has been given in six women of 45 patients with a GCT who were referred for treatment or judgment in the Institut Gustave Roussy of Villejuif. Inhibin remained undetectable in four patients without evidence of disease. In one of them, inhibin level decreased progressively after surgical resection (for 10 months). Inhibin was also given in two patients with recurrence: in one case inhibin level was very high, and in one case it was barely detectable. In finding with other publications, inhibin can be used as a maker for recourent disease, when patients are menopaused even when tumor does not produce steroids.