Intricate Links between ER Stress and Apoptosis

Frank Madeo; Guido Kroemer

doi:10.1016/j.molcel.2009.03.002

Intricate Links between ER Stress and Apoptosis

Frank Madeo, Guido Kroemer

Résultats de recherche: Contribution à un journal › Brève enquête › Revue par des pairs

37 Citations (Scopus)

Résumé

Bax inhibitor-1 (BI-1) interacts with Bax, neutralizing its proapoptotic activity. In this issue of Molecular Cell, Lisbona et al. (2009) show that BI-1 directly inhibits IRE1α, an essential mediator of the UPR, thereby facilitating crosstalk between apoptosis and ER stress pathways.

langue originale	Anglais
Pages (de - à)	669-670
Nombre de pages	2
journal	Molecular Cell
Volume	33
Numéro de publication	6
Les DOIs	https://doi.org/10.1016/j.molcel.2009.03.002
état	Publié - 27 mars 2009

Accès au document

10.1016/j.molcel.2009.03.002

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Contient cette citation

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title = "Intricate Links between ER Stress and Apoptosis",

abstract = "Bax inhibitor-1 (BI-1) interacts with Bax, neutralizing its proapoptotic activity. In this issue of Molecular Cell, Lisbona et al. (2009) show that BI-1 directly inhibits IRE1α, an essential mediator of the UPR, thereby facilitating crosstalk between apoptosis and ER stress pathways.",

author = "Frank Madeo and Guido Kroemer",

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AU - Madeo, Frank

AU - Kroemer, Guido

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AB - Bax inhibitor-1 (BI-1) interacts with Bax, neutralizing its proapoptotic activity. In this issue of Molecular Cell, Lisbona et al. (2009) show that BI-1 directly inhibits IRE1α, an essential mediator of the UPR, thereby facilitating crosstalk between apoptosis and ER stress pathways.

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DO - 10.1016/j.molcel.2009.03.002

M3 - Short survey

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AN - SCOPUS:62549154503

SN - 1097-2765

VL - 33

SP - 669

EP - 670

JO - Molecular Cell

JF - Molecular Cell

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