Résumé
Bax inhibitor-1 (BI-1) interacts with Bax, neutralizing its proapoptotic activity. In this issue of Molecular Cell, Lisbona et al. (2009) show that BI-1 directly inhibits IRE1α, an essential mediator of the UPR, thereby facilitating crosstalk between apoptosis and ER stress pathways.
langue originale | Anglais |
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Pages (de - à) | 669-670 |
Nombre de pages | 2 |
journal | Molecular Cell |
Volume | 33 |
Numéro de publication | 6 |
Les DOIs | |
état | Publié - 27 mars 2009 |