TY - JOUR
T1 - Late recurrence or secondary location? Towards a better understanding of the physiopathology of inverted papilloma
AU - Prud'Homme, C.
AU - Espinoza, S.
AU - Badoual, C.
AU - Laccourreye, O.
AU - Bonfils, P.
AU - Malinvaud, D.
PY - 2013/11/1
Y1 - 2013/11/1
N2 - Introduction: Inverted papilloma (IP) is the most frequent benign tumor of the nasal cavities. Recurrence is found in 12 to 14% of cases, mainly at the primary site, although also exceptionally in remote locations. The present paper discusses the physiopathogenesis of IP on the basis of a report of late second occurrence of IP at a remote location and a review of the literature. Case report: A man, who had undergone surgery in 1997 for ethmoid IP at the age of 56, presented 11 years later with nasal cavity IP at a second (frontal) location, discovered serendipitously during systematic follow-up and managed surgically without complication. Discussion and conclusion: The physiopathology of nasal cavity IP remains unexplained. No reliable histologic or biological markers predict risk of recurrence or of malignant transformation. The sole treatment is total surgical resection. The risk of local recurrence, often due to incomplete resection, is well known, but that of a secondary location is less so, and regular very long-term follow-up is justified.
AB - Introduction: Inverted papilloma (IP) is the most frequent benign tumor of the nasal cavities. Recurrence is found in 12 to 14% of cases, mainly at the primary site, although also exceptionally in remote locations. The present paper discusses the physiopathogenesis of IP on the basis of a report of late second occurrence of IP at a remote location and a review of the literature. Case report: A man, who had undergone surgery in 1997 for ethmoid IP at the age of 56, presented 11 years later with nasal cavity IP at a second (frontal) location, discovered serendipitously during systematic follow-up and managed surgically without complication. Discussion and conclusion: The physiopathology of nasal cavity IP remains unexplained. No reliable histologic or biological markers predict risk of recurrence or of malignant transformation. The sole treatment is total surgical resection. The risk of local recurrence, often due to incomplete resection, is well known, but that of a secondary location is less so, and regular very long-term follow-up is justified.
KW - Endoscopic surgery
KW - Inverted papilloma
KW - Recurrence
KW - Remote location
KW - Sinus
UR - http://www.scopus.com/inward/record.url?scp=84887254159&partnerID=8YFLogxK
U2 - 10.1016/j.anorl.2012.11.004
DO - 10.1016/j.anorl.2012.11.004
M3 - Article
C2 - 23890789
AN - SCOPUS:84887254159
SN - 1879-7296
VL - 130
SP - 289
EP - 291
JO - European Annals of Otorhinolaryngology, Head and Neck Diseases
JF - European Annals of Otorhinolaryngology, Head and Neck Diseases
IS - 5
ER -