Le ganglion sentinelle dans le cancer du sein: Aspects cliniques

Roman Rouzier, Jean Paul Travagli, David Atallah, Suzette Delaloge, Hugo Marsiglia, Marie Christine Mathieu, Jean Lumbroso, Jean Rémi Garbay

    Résultats de recherche: Contribution à un journalArticle 'review'Revue par des pairs

    2 Citations (Scopus)

    Résumé

    Sentinel lymph node (SLN) biopsy is effective to assess axillary nodal status and avoiding axillary lymph node dissection (ALND) in patients with clinically node-negative early stage breast cancer. No standardization of the technique has yet been established. This review discusses the feasibility, the accuracy and the different techniques for this procedure. Although the SLN can be successfully identified by either the dye or gamma probe-guided method, its identification is facilitated when the two techniques are combined. To increase the sensitivity of the pathological examination of the SLN, it is necessary to make multiple step sections with hematoxylin and eosin staining immunohistochemistry on permanent sections. The intraoperative frozen sections and imprint cytology examinations of the SLN may be useful in determining its status, but further studies are needed to establish their performance. In clinical practice, routine ALND can be avoided for small tumours when the multidisciplinary team has an extensive experience of this technique. However, long-term regional control and survival have to be studied in prospective randomised trials, before SLN biopsy can replace routine ALND as the preferred staging method for women with localized breast cancer.

    Titre traduit de la contributionSentinel node biopsy in breast cancer: Clinical aspects
    langue originaleFrançais
    Pages (de - à)246-254
    Nombre de pages9
    journalBulletin du Cancer
    Volume90
    Numéro de publication3
    étatPublié - 1 mars 2003

    mots-clés

    • Axillary lymph node dissection
    • Breast neoplasms
    • Cancer
    • Sentinel lymph node

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