Life threatening bleeding from an osteonecrosis of the jaw: Are bisphosphonates safe in irradiated head and neck cancer patients?

Tarek Assi, Ralph Chebib, Sara Lakiss, Joseph Kattan

Résultats de recherche: Contribution à un journalArticleRevue par des pairs

Résumé

Osteonecrosis of the jaw is a significant complication secondary to radiation therapy or drug therapy, most commonly bisphosphonates. Safety data regarding the administration of bisphosphonates in bone metastatic head and neck cancer patients with history of jaw irradiation are almost non-existent. In this paper, we report the case of a Head and Neck (HNC) patient, with history of radiation therapy to the mandible region, treated with intravenous bisphosphonates for bone metastases that resulted in gross, life threatening mouth hemorrhage secondary to advanced, locally invasive ONJ.

langue originaleAnglais
Pages (de - à)72-74
Nombre de pages3
journalThe Gulf journal of oncology
Volume1
Numéro de publication28
étatPublié - 1 sept. 2018
Modification externeOui

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