Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol

A. Dinnoo; F. Bidault; N. Lassau; M. Elmaalouf; A. Moya-Plana; A. Ruffier; F. Janot; N. Benmoussa

doi:10.1016/j.jormas.2019.06.007

Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol

A. Dinnoo, F. Bidault, N. Lassau, M. Elmaalouf, A. Moya-Plana, A. Ruffier, F. Janot, N. Benmoussa

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

3 Citations (Scopus)

Résumé

Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end.

langue originale	Anglais
Pages (de - à)	286-287
Nombre de pages	2
journal	Journal of Stomatology, Oral and Maxillofacial Surgery
Volume	121
Numéro de publication	3
Les DOIs	https://doi.org/10.1016/j.jormas.2019.06.007
état	Publié - 1 juin 2020

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10.1016/j.jormas.2019.06.007

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title = "Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol",

abstract = "Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end.",

keywords = "Osteoradionecrosis, PENTO, PENTOCLO",

author = "A. Dinnoo and F. Bidault and N. Lassau and M. Elmaalouf and A. Moya-Plana and A. Ruffier and F. Janot and N. Benmoussa",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Masson SAS",

year = "2020",

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doi = "10.1016/j.jormas.2019.06.007",

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T1 - Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol

AU - Dinnoo, A.

AU - Bidault, F.

AU - Lassau, N.

AU - Elmaalouf, M.

AU - Moya-Plana, A.

AU - Ruffier, A.

AU - Janot, F.

AU - Benmoussa, N.

PY - 2020/6/1

Y1 - 2020/6/1

N2 - Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end.

AB - Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end.

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