Macrophages in radiation injury: a new therapeutic target

Lydia Meziani; Eric Deutsch; Michele Mondini

doi:10.1080/2162402X.2018.1494488

Macrophages in radiation injury: a new therapeutic target

Lydia Meziani, Eric Deutsch, Michele Mondini

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

51 Citations (Scopus)

Résumé

Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.

langue originale	Anglais
Numéro d'article	e1494488
journal	OncoImmunology
Volume	7
Numéro de publication	10
Les DOIs	https://doi.org/10.1080/2162402X.2018.1494488
état	Publié - 3 oct. 2018

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10.1080/2162402X.2018.1494488

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@article{65d152affa6d4632af9f518a1056a31c,

title = "Macrophages in radiation injury: a new therapeutic target",

abstract = "Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.",

keywords = "Radiation injury, immune system, lung fibrosis, macrophages, radiation toxicity",

author = "Lydia Meziani and Eric Deutsch and Michele Mondini",

note = "Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Taylor & Francis Group, LLC.",

year = "2018",

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AU - Meziani, Lydia

AU - Deutsch, Eric

AU - Mondini, Michele

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N2 - Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.

AB - Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.

KW - Radiation injury

KW - immune system

KW - lung fibrosis

KW - macrophages

KW - radiation toxicity

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DO - 10.1080/2162402X.2018.1494488

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