Management of melanoma brain metastasis

C. Boutros; C. Robert

doi:10.1007/978-3-030-23417-1_22

Management of melanoma brain metastasis

C. Boutros, C. Robert

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Chapter › Revue par des pairs

Résumé

In the past decades, local therapies including surgery, whole-brain radiation therapy, and stereotactic radiosurgery were considered the pillar of metastatic brain metastasis (MBM) management, although their benefit in terms of overall survival was never demonstrated. Advances in understanding the biology and molecular pathways implicated in melanoma biology and consecutive improvements in metastatic melanoma treatment using anti-BRAF-based targeted therapies for BRAFV600-mutant melanoma as well as immune checkpoint immunotherapy have generated considerable interest in evaluating these novel systemic therapies in treating MBM (Table 22.1).

langue originale	Anglais
titre	Central Nervous System Metastases
Editeur	Springer International Publishing
Pages	281-287
Nombre de pages	7
ISBN (Electronique)	9783030234171
ISBN (imprimé)	9783030234164
Les DOIs	https://doi.org/10.1007/978-3-030-23417-1_22
état	Publié - 1 janv. 2019

Accès au document

10.1007/978-3-030-23417-1_22

Autres fichiers et liens

Lien vers la publication dans Scopus

Contient cette citation

@inbook{281949ebcf354f0488222cf631b33df7,

title = "Management of melanoma brain metastasis",

abstract = "In the past decades, local therapies including surgery, whole-brain radiation therapy, and stereotactic radiosurgery were considered the pillar of metastatic brain metastasis (MBM) management, although their benefit in terms of overall survival was never demonstrated. Advances in understanding the biology and molecular pathways implicated in melanoma biology and consecutive improvements in metastatic melanoma treatment using anti-BRAF-based targeted therapies for BRAFV600-mutant melanoma as well as immune checkpoint immunotherapy have generated considerable interest in evaluating these novel systemic therapies in treating MBM (Table 22.1).",

author = "C. Boutros and C. Robert",

note = "Publisher Copyright: {\textcopyright} Springer Nature Switzerland AG 2020.",

year = "2019",

month = jan,

day = "1",

doi = "10.1007/978-3-030-23417-1_22",

language = "English",

isbn = "9783030234164",

pages = "281--287",

booktitle = "Central Nervous System Metastases",

publisher = "Springer International Publishing",

}

TY - CHAP

T1 - Management of melanoma brain metastasis

AU - Boutros, C.

AU - Robert, C.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - In the past decades, local therapies including surgery, whole-brain radiation therapy, and stereotactic radiosurgery were considered the pillar of metastatic brain metastasis (MBM) management, although their benefit in terms of overall survival was never demonstrated. Advances in understanding the biology and molecular pathways implicated in melanoma biology and consecutive improvements in metastatic melanoma treatment using anti-BRAF-based targeted therapies for BRAFV600-mutant melanoma as well as immune checkpoint immunotherapy have generated considerable interest in evaluating these novel systemic therapies in treating MBM (Table 22.1).

AB - In the past decades, local therapies including surgery, whole-brain radiation therapy, and stereotactic radiosurgery were considered the pillar of metastatic brain metastasis (MBM) management, although their benefit in terms of overall survival was never demonstrated. Advances in understanding the biology and molecular pathways implicated in melanoma biology and consecutive improvements in metastatic melanoma treatment using anti-BRAF-based targeted therapies for BRAFV600-mutant melanoma as well as immune checkpoint immunotherapy have generated considerable interest in evaluating these novel systemic therapies in treating MBM (Table 22.1).

UR - http://www.scopus.com/inward/record.url?scp=85086960306&partnerID=8YFLogxK

U2 - 10.1007/978-3-030-23417-1_22

DO - 10.1007/978-3-030-23417-1_22

M3 - Chapter

AN - SCOPUS:85086960306

SN - 9783030234164

SP - 281

EP - 287

BT - Central Nervous System Metastases

PB - Springer International Publishing

ER -