Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck: A Comprehensive Review †

Beatriz G. Cavalheiro; Jatin P. Shah; Gregory W. Randolph; Jesus E. Medina; Ralph P. Tufano; Mark Zafereo; Dana M. Hartl; Iain J. Nixon; Orlando Guntinas-Lichius; Vincent Vander Poorten; Fernando López; Avi Hefetz Khafif; Randall P. Owen; Ashok Shaha; Juan P. Rodrigo; Alessandra Rinaldo; Antti A. Mäkitie; Carl E. Silver; Alvaro Sanabria; Luiz P. Kowalski; Alfio Ferlito

doi:10.3390/cancers15030923

Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck: A Comprehensive Review †

Beatriz G. Cavalheiro, Jatin P. Shah, Gregory W. Randolph, Jesus E. Medina, Ralph P. Tufano, Mark Zafereo, Dana M. Hartl, Iain J. Nixon, Orlando Guntinas-Lichius, Vincent Vander Poorten, Fernando López, Avi Hefetz Khafif, Randall P. Owen, Ashok Shaha, Juan P. Rodrigo, Alessandra Rinaldo, Antti A. Mäkitie, Carl E. Silver, Alvaro Sanabria, Luiz P. KowalskiAlfio Ferlito

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

9 Citations (Scopus)

Résumé

Surgery has been historically the preferred primary treatment for patients with well-differentiated thyroid carcinoma and for selected locoregional recurrences. Adjuvant therapy with radioactive iodine is typically recommended for patients with an intermediate to high risk of recurrence. Despite these treatments, locally advanced disease and locoregional relapses are not infrequent. These patients have a prolonged overall survival that may result in long periods of active disease and the possibility of requiring subsequent treatments. Recently, many new options have emerged as salvage therapies. This review offers a comprehensive discussion and considerations regarding surgery, active surveillance, radioactive iodine therapy, ultrasonography-guided percutaneous ablation, external beam radiotherapy, and systemic therapy for well-differentiated thyroid cancer based on relevant publications and current reference guidelines. We feel that the surgical member of the thyroid cancer management team is empowered by being aware and facile with all management options.

langue originale	Anglais
Numéro d'article	923
journal	Cancers
Volume	15
Numéro de publication	3
Les DOIs	https://doi.org/10.3390/cancers15030923
état	Publié - 1 févr. 2023

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10.3390/cancers15030923

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Cavalheiro, B. G., Shah, J. P., Randolph, G. W., Medina, J. E., Tufano, R. P., Zafereo, M., Hartl, D. M., Nixon, I. J., Guntinas-Lichius, O., Vander Poorten, V., López, F., Khafif, A. H., Owen, R. P., Shaha, A., Rodrigo, J. P., Rinaldo, A., Mäkitie, A. A., Silver, C. E., Sanabria, A., ... Ferlito, A. (2023). Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck: A Comprehensive Review †. Cancers, 15(3), Article 923. https://doi.org/10.3390/cancers15030923

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title = "Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck: A Comprehensive Review †",

abstract = "Surgery has been historically the preferred primary treatment for patients with well-differentiated thyroid carcinoma and for selected locoregional recurrences. Adjuvant therapy with radioactive iodine is typically recommended for patients with an intermediate to high risk of recurrence. Despite these treatments, locally advanced disease and locoregional relapses are not infrequent. These patients have a prolonged overall survival that may result in long periods of active disease and the possibility of requiring subsequent treatments. Recently, many new options have emerged as salvage therapies. This review offers a comprehensive discussion and considerations regarding surgery, active surveillance, radioactive iodine therapy, ultrasonography-guided percutaneous ablation, external beam radiotherapy, and systemic therapy for well-differentiated thyroid cancer based on relevant publications and current reference guidelines. We feel that the surgical member of the thyroid cancer management team is empowered by being aware and facile with all management options.",

keywords = "metastasis, molecular targeted therapy, neck dissection, neoadjuvant therapy, papillary thyroid cancer, radiofrequency ablation, radiotherapy, recurrence, surgery, thyroid neoplasm",

author = "Cavalheiro, {Beatriz G.} and Shah, {Jatin P.} and Randolph, {Gregory W.} and Medina, {Jesus E.} and Tufano, {Ralph P.} and Mark Zafereo and Hartl, {Dana M.} and Nixon, {Iain J.} and Orlando Guntinas-Lichius and {Vander Poorten}, Vincent and Fernando L{\'o}pez and Khafif, {Avi Hefetz} and Owen, {Randall P.} and Ashok Shaha and Rodrigo, {Juan P.} and Alessandra Rinaldo and M{\"a}kitie, {Antti A.} and Silver, {Carl E.} and Alvaro Sanabria and Kowalski, {Luiz P.} and Alfio Ferlito",

note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

month = feb,

day = "1",

doi = "10.3390/cancers15030923",

language = "English",

volume = "15",

journal = "Cancers",

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Cavalheiro, BG, Shah, JP, Randolph, GW, Medina, JE, Tufano, RP, Zafereo, M, Hartl, DM, Nixon, IJ, Guntinas-Lichius, O, Vander Poorten, V, López, F, Khafif, AH, Owen, RP, Shaha, A, Rodrigo, JP, Rinaldo, A, Mäkitie, AA, Silver, CE, Sanabria, A, Kowalski, LP & Ferlito, A 2023, 'Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck: A Comprehensive Review †', Cancers, VOL. 15, Numéro 3, 923. https://doi.org/10.3390/cancers15030923

TY - JOUR

T1 - Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck

T2 - A Comprehensive Review †

AU - Cavalheiro, Beatriz G.

AU - Shah, Jatin P.

AU - Randolph, Gregory W.

AU - Medina, Jesus E.

AU - Tufano, Ralph P.

AU - Zafereo, Mark

AU - Hartl, Dana M.

AU - Nixon, Iain J.

AU - Guntinas-Lichius, Orlando

AU - Vander Poorten, Vincent

AU - López, Fernando

AU - Khafif, Avi Hefetz

AU - Owen, Randall P.

AU - Shaha, Ashok

AU - Rodrigo, Juan P.

AU - Rinaldo, Alessandra

AU - Mäkitie, Antti A.

AU - Silver, Carl E.

AU - Sanabria, Alvaro

AU - Kowalski, Luiz P.

AU - Ferlito, Alfio

PY - 2023/2/1

Y1 - 2023/2/1

N2 - Surgery has been historically the preferred primary treatment for patients with well-differentiated thyroid carcinoma and for selected locoregional recurrences. Adjuvant therapy with radioactive iodine is typically recommended for patients with an intermediate to high risk of recurrence. Despite these treatments, locally advanced disease and locoregional relapses are not infrequent. These patients have a prolonged overall survival that may result in long periods of active disease and the possibility of requiring subsequent treatments. Recently, many new options have emerged as salvage therapies. This review offers a comprehensive discussion and considerations regarding surgery, active surveillance, radioactive iodine therapy, ultrasonography-guided percutaneous ablation, external beam radiotherapy, and systemic therapy for well-differentiated thyroid cancer based on relevant publications and current reference guidelines. We feel that the surgical member of the thyroid cancer management team is empowered by being aware and facile with all management options.

AB - Surgery has been historically the preferred primary treatment for patients with well-differentiated thyroid carcinoma and for selected locoregional recurrences. Adjuvant therapy with radioactive iodine is typically recommended for patients with an intermediate to high risk of recurrence. Despite these treatments, locally advanced disease and locoregional relapses are not infrequent. These patients have a prolonged overall survival that may result in long periods of active disease and the possibility of requiring subsequent treatments. Recently, many new options have emerged as salvage therapies. This review offers a comprehensive discussion and considerations regarding surgery, active surveillance, radioactive iodine therapy, ultrasonography-guided percutaneous ablation, external beam radiotherapy, and systemic therapy for well-differentiated thyroid cancer based on relevant publications and current reference guidelines. We feel that the surgical member of the thyroid cancer management team is empowered by being aware and facile with all management options.

KW - metastasis

KW - molecular targeted therapy

KW - neck dissection

KW - neoadjuvant therapy

KW - papillary thyroid cancer

KW - radiofrequency ablation

KW - radiotherapy

KW - recurrence

KW - surgery

KW - thyroid neoplasm

UR - http://www.scopus.com/inward/record.url?scp=85147831995&partnerID=8YFLogxK

U2 - 10.3390/cancers15030923

DO - 10.3390/cancers15030923

M3 - Review article

AN - SCOPUS:85147831995

SN - 2072-6694

VL - 15

JO - Cancers

JF - Cancers

IS - 3

M1 - 923

ER -