Management of the Neck in Well-Differentiated Thyroid Cancer

Panagiotis Asimakopoulos; Ashok R. Shaha; Iain J. Nixon; Jatin P. Shah; Gregory W. Randolph; Peter Angelos; Mark E. Zafereo; Luiz P. Kowalski; Dana M. Hartl; Kerry D. Olsen; Juan P. Rodrigo; Vincent Vander Poorten; Antti A. Mäkitie; Alvaro Sanabria; Carlos Suárez; Miquel Quer; Francisco J. Civantos; K. Thomas Robbins; Orlando Guntinas-Lichius; Marc Hamoir; Alessandra Rinaldo; Alfio Ferlito

doi:10.1007/s11912-020-00997-6

Management of the Neck in Well-Differentiated Thyroid Cancer

Panagiotis Asimakopoulos, Ashok R. Shaha, Iain J. Nixon, Jatin P. Shah, Gregory W. Randolph, Peter Angelos, Mark E. Zafereo, Luiz P. Kowalski, Dana M. Hartl, Kerry D. Olsen, Juan P. Rodrigo, Vincent Vander Poorten, Antti A. Mäkitie, Alvaro Sanabria, Carlos Suárez, Miquel Quer, Francisco J. Civantos, K. Thomas Robbins, Orlando Guntinas-Lichius, Marc HamoirAlessandra Rinaldo, Alfio Ferlito

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

27 Citations (Scopus)

Résumé

Purpose of Review: In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer. Recent Findings: Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. Summary: As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.

langue originale	Anglais
Numéro d'article	1
journal	Current Oncology Reports
Volume	23
Numéro de publication	1
Les DOIs	https://doi.org/10.1007/s11912-020-00997-6
état	Publié - 1 janv. 2021

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10.1007/s11912-020-00997-6

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Asimakopoulos, P., Shaha, A. R., Nixon, I. J., Shah, J. P., Randolph, G. W., Angelos, P., Zafereo, M. E., Kowalski, L. P., Hartl, D. M., Olsen, K. D., Rodrigo, J. P., Vander Poorten, V., Mäkitie, A. A., Sanabria, A., Suárez, C., Quer, M., Civantos, F. J., Robbins, K. T., Guntinas-Lichius, O., ... Ferlito, A. (2021). Management of the Neck in Well-Differentiated Thyroid Cancer. Current Oncology Reports, 23(1), Article 1. https://doi.org/10.1007/s11912-020-00997-6

@article{abecce9b690a4bb6969c1f9afb07fa61,

title = "Management of the Neck in Well-Differentiated Thyroid Cancer",

abstract = "Purpose of Review: In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer. Recent Findings: Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. Summary: As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.",

keywords = "Lymphatic metastasis, Neck dissection, Thyroid neoplasms",

author = "Panagiotis Asimakopoulos and Shaha, {Ashok R.} and Nixon, {Iain J.} and Shah, {Jatin P.} and Randolph, {Gregory W.} and Peter Angelos and Zafereo, {Mark E.} and Kowalski, {Luiz P.} and Hartl, {Dana M.} and Olsen, {Kerry D.} and Rodrigo, {Juan P.} and {Vander Poorten}, Vincent and M{\"a}kitie, {Antti A.} and Alvaro Sanabria and Carlos Su{\'a}rez and Miquel Quer and Civantos, {Francisco J.} and Robbins, {K. Thomas} and Orlando Guntinas-Lichius and Marc Hamoir and Alessandra Rinaldo and Alfio Ferlito",

note = "Publisher Copyright: {\textcopyright} 2020, Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2021",

month = jan,

day = "1",

doi = "10.1007/s11912-020-00997-6",

language = "English",

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Asimakopoulos, P, Shaha, AR, Nixon, IJ, Shah, JP, Randolph, GW, Angelos, P, Zafereo, ME, Kowalski, LP, Hartl, DM, Olsen, KD, Rodrigo, JP, Vander Poorten, V, Mäkitie, AA, Sanabria, A, Suárez, C, Quer, M, Civantos, FJ, Robbins, KT, Guntinas-Lichius, O, Hamoir, M, Rinaldo, A & Ferlito, A 2021, 'Management of the Neck in Well-Differentiated Thyroid Cancer', Current Oncology Reports, VOL. 23, Numéro 1, 1. https://doi.org/10.1007/s11912-020-00997-6

TY - JOUR

T1 - Management of the Neck in Well-Differentiated Thyroid Cancer

AU - Asimakopoulos, Panagiotis

AU - Shaha, Ashok R.

AU - Nixon, Iain J.

AU - Shah, Jatin P.

AU - Randolph, Gregory W.

AU - Angelos, Peter

AU - Zafereo, Mark E.

AU - Kowalski, Luiz P.

AU - Hartl, Dana M.

AU - Olsen, Kerry D.

AU - Rodrigo, Juan P.

AU - Vander Poorten, Vincent

AU - Mäkitie, Antti A.

AU - Sanabria, Alvaro

AU - Suárez, Carlos

AU - Quer, Miquel

AU - Civantos, Francisco J.

AU - Robbins, K. Thomas

AU - Guntinas-Lichius, Orlando

AU - Hamoir, Marc

AU - Rinaldo, Alessandra

AU - Ferlito, Alfio

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Purpose of Review: In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer. Recent Findings: Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. Summary: As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.

AB - Purpose of Review: In this narrative review, we discuss the indications for elective and therapeutic neck dissections and the postoperative surveillance and treatment options for recurrent nodal disease in patients with well-differentiated thyroid cancer. Recent Findings: Increased availability of advanced imaging modalities has led to an increased detection rate of previously occult nodal disease in thyroid cancer. Nodal metastases are more common in young patients, large primary tumors, specific genotypes, and certain histological types. While clinically evident nodal disease in the lateral neck compartments has a significant oncological impact, particularly in the older age group, microscopic metastases to the central or the lateral neck in well-differentiated thyroid cancer do not significantly affect outcome. Summary: As patients with clinically evident nodal disease are associated with worse outcomes, they should be treated surgically in order to reduce rates of regional recurrence and improve survival. The benefit of elective neck dissection remains unverified as the impact of microscopic disease on outcomes is not significant.

KW - Lymphatic metastasis

KW - Neck dissection

KW - Thyroid neoplasms

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U2 - 10.1007/s11912-020-00997-6

DO - 10.1007/s11912-020-00997-6

M3 - Review article

C2 - 33190176

AN - SCOPUS:85095950778

SN - 1523-3790

VL - 23

JO - Current Oncology Reports

JF - Current Oncology Reports

IS - 1

M1 - 1

ER -