Résumé
It has been a long-standing enigma which scramblase causes phosphatidylserine residues to be exposed on the surface of apoptotic cells, thereby facilitating the phagocytic recognition, engulfment and destruction of apoptotic corpses. In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C. elegans ortholog, CED-8, are activated by caspase cleavage in apoptotic cells.
langue originale | Anglais |
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Pages (de - à) | 1247-1248 |
Nombre de pages | 2 |
journal | Cell Research |
Volume | 23 |
Numéro de publication | 11 |
Les DOIs | |
état | Publié - 1 nov. 2013 |