Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum

Agnese Denzi; Hanna Hanna; Franck M. Andre; Lluis M. Mir; Francesca Apollonio; Micaela Liberti

doi:10.1109/SMACD.2017.7981606

Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum

Agnese Denzi, Hanna Hanna, Franck M. Andre, Lluis M. Mir, Francesca Apollonio, Micaela Liberti

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Conference contribution › Revue par des pairs

3 Citations (Scopus)

Résumé

Microsecond pulsed electric fields (μsPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of μsPEFs also for the permeabilization of this internal structure.

langue originale	Anglais
titre	SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design
Editeur	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronique)	9781509050529
Les DOIs	https://doi.org/10.1109/SMACD.2017.7981606
état	Publié - 14 juil. 2017
Modification externe	Oui
Evénement	14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017 - Giardini Naxos, Taormina, Italie Durée: 12 juin 2017 → 15 juin 2017

Série de publications

Nom	SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design

Une conférence

Une conférence	14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017
Pays/Territoire	Italie
La ville	Giardini Naxos, Taormina
période	12/06/17 → 15/06/17

Accès au document

10.1109/SMACD.2017.7981606

Autres fichiers et liens

Lien vers la publication dans Scopus

Contient cette citation

Denzi, A., Hanna, H., Andre, F. M., Mir, L. M., Apollonio, F., & Liberti, M. (2017). Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum. Dans SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design Article 7981606 (SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SMACD.2017.7981606

Denzi, Agnese ; Hanna, Hanna ; Andre, Franck M. et al. / Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum. SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design. Institute of Electrical and Electronics Engineers Inc., 2017. (SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design).

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title = "Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum",

abstract = "Microsecond pulsed electric fields (μsPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of μsPEFs also for the permeabilization of this internal structure.",

keywords = "electropermeabilization, electroporation, electropulsation, endoplamic reticulum, mesenchymal stem cells, microsecond pulsed electric field",

author = "Agnese Denzi and Hanna Hanna and Andre, {Franck M.} and Mir, {Lluis M.} and Francesca Apollonio and Micaela Liberti",

note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017 ; Conference date: 12-06-2017 Through 15-06-2017",

year = "2017",

month = jul,

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doi = "10.1109/SMACD.2017.7981606",

language = "English",

series = "SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

booktitle = "SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design",

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Denzi, A, Hanna, H, Andre, FM, Mir, LM, Apollonio, F & Liberti, M 2017, Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum. Dans SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design., 7981606, SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, Institute of Electrical and Electronics Engineers Inc., 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017, Giardini Naxos, Taormina, Italie, 12/06/17. https://doi.org/10.1109/SMACD.2017.7981606

Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum. / Denzi, Agnese; Hanna, Hanna; Andre, Franck M. et al.
SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design. Institute of Electrical and Electronics Engineers Inc., 2017. 7981606 (SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design).

Résultats de recherche: Le chapitre dans un livre, un rapport, une anthologie ou une collection › !!Conference contribution › Revue par des pairs

TY - GEN

T1 - Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum

AU - Denzi, Agnese

AU - Hanna, Hanna

AU - Andre, Franck M.

AU - Mir, Lluis M.

AU - Apollonio, Francesca

AU - Liberti, Micaela

PY - 2017/7/14

Y1 - 2017/7/14

N2 - Microsecond pulsed electric fields (μsPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of μsPEFs also for the permeabilization of this internal structure.

AB - Microsecond pulsed electric fields (μsPEFs) with amplitude of tens of kV/m are used to permeabilize the plasma membrane whereas nanosecond pulsed electric fields of MV/m also permeabilize cell internal structures, such as the endoplasmic reticulum. In this work, a numerical realistic model of cell and its reticulum has been realized to study the use of μsPEFs also for the permeabilization of this internal structure.

KW - electropermeabilization

KW - electroporation

KW - electropulsation

KW - endoplamic reticulum

KW - mesenchymal stem cells

KW - microsecond pulsed electric field

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U2 - 10.1109/SMACD.2017.7981606

DO - 10.1109/SMACD.2017.7981606

M3 - Conference contribution

AN - SCOPUS:85027503280

T3 - SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design

BT - SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design, SMACD 2017

Y2 - 12 June 2017 through 15 June 2017

ER -

Denzi A, Hanna H, Andre FM, Mir LM, Apollonio F, Liberti M. Microdosimetry for pulsed e fields in a realistic models of cells and endoplasmic reticulum. Dans SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design. Institute of Electrical and Electronics Engineers Inc. 2017. 7981606. (SMACD 2017 - 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design). doi: 10.1109/SMACD.2017.7981606