@article{e1e05c7f2b84407ea1c2f215f1e89d95,
title = "Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration",
abstract = "Whether microglia that reside in different central nervous system niches have distinct functions is unclear. O'Koren and Yu et al. now reveal key functional differences in microglia across two anatomically distinct locations in the retina during homeostasis. Furthermore, in degenerative conditions, microglia migrate to another location where they undergo transcriptional reprogramming and contribute to retinal cytoprotection.",
keywords = "IL-34, macrophages, microglia, microglial heterogeneity, phagocytes, retinal degeneration, retinitis pigmentosa",
author = "O'Koren, {Emily G.} and Chen Yu and Mikael Klingeborn and Wong, {Alicia Y.W.} and Prigge, {Cameron L.} and Rose Mathew and Joan Kalnitsky and Msallam, {Rasha A.} and Aymeric Silvin and Kay, {Jeremy N.} and {Bowes Rickman}, Catherine and Arshavsky, {Vadim Y.} and Florent Ginhoux and Miriam Merad and Saban, {Daniel R.}",
note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = mar,
day = "19",
doi = "10.1016/j.immuni.2019.02.007",
language = "English",
volume = "50",
pages = "723--737.e7",
journal = "Immunity",
issn = "1074-7613",
number = "3",
}