TY - GEN
T1 - Multimodal Brain Tumor Classification
AU - Lerousseau, Marvin
AU - Deutsch, Eric
AU - Paragios, Nikos
N1 - Publisher Copyright:
© 2021, Springer Nature Switzerland AG.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional knowledge towards the efficacy of cancer diagnostics. This work investigates a deep learning method combining whole slide images and magnetic resonance images to classify tumors. In particular, our solution comprises a powerful, generic and modular architecture for whole slide image classification. Experiments are prospectively conducted on the 2020 Computational Precision Medicine challenge, in a 3-classes unbalanced classification task. We report cross-validation (resp. validation) balanced-accuracy, kappa and f1 of 0.913, 0.897 and 0.951 (resp. 0.91, 0.90 and 0.94). For research purposes, including reproducibility and direct performance comparisons, our finale submitted models are usable off-the-shelf in a Docker image available at https://hub.docker.com/repository/docker/marvinler/cpm_2020_marvinler.
AB - Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional knowledge towards the efficacy of cancer diagnostics. This work investigates a deep learning method combining whole slide images and magnetic resonance images to classify tumors. In particular, our solution comprises a powerful, generic and modular architecture for whole slide image classification. Experiments are prospectively conducted on the 2020 Computational Precision Medicine challenge, in a 3-classes unbalanced classification task. We report cross-validation (resp. validation) balanced-accuracy, kappa and f1 of 0.913, 0.897 and 0.951 (resp. 0.91, 0.90 and 0.94). For research purposes, including reproducibility and direct performance comparisons, our finale submitted models are usable off-the-shelf in a Docker image available at https://hub.docker.com/repository/docker/marvinler/cpm_2020_marvinler.
KW - CPM RadPath
KW - Histopathological classification
KW - Multimodal classification
KW - Radiology classification
KW - Tumor classification
UR - http://www.scopus.com/inward/record.url?scp=85107334300&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-72087-2_42
DO - 10.1007/978-3-030-72087-2_42
M3 - Conference contribution
AN - SCOPUS:85107334300
SN - 9783030720865
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 475
EP - 486
BT - Brainlesion
A2 - Crimi, Alessandro
A2 - Bakas, Spyridon
PB - Springer Science and Business Media Deutschland GmbH
T2 - 6th International MICCAI Brainlesion Workshop, BrainLes 2020 Held in Conjunction with 23rd Medical Image Computing for Computer Assisted Intervention Conference, MICCAI 2020
Y2 - 4 October 2020 through 4 October 2020
ER -