Oncogènes et tumeurs de la thyroïde

Ludovic Lacroix; Jean Charles Soria; Jean Michel Bidart; Martin Schlumberger

Oncogènes et tumeurs de la thyroïde

Ludovic Lacroix, Jean Charles Soria, Jean Michel Bidart, Martin Schlumberger

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

12 Citations (Scopus)

Résumé

Papillary thyroid carcinomas are characterized in 70% of cases by the presence of either a RET/PTC rearrangement, or an activating point mutation of RAS or BRAF genes that induce a constitutive activation of the MAP kinase pathway. Follicular carcinomas are characterized by the presence of a RAS mutation or of a PAX8-PPARγ rearrangement. Inactivating mutations of the p53 gene are found only in anaplastic thyroid carcinomas.

Titre traduit de la contribution	Oncogenes and thyroid tumors
langue originale	Français
Pages (de - à)	37-43
Nombre de pages	7
journal	Bulletin du Cancer
Volume	92
Numéro de publication	1
état	Publié - 1 janv. 2005

mots-clés

Oncogen
Thyroid carcinoma

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Contient cette citation

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title = "Oncog{\`e}nes et tumeurs de la thyro{\"i}de",

abstract = "Papillary thyroid carcinomas are characterized in 70% of cases by the presence of either a RET/PTC rearrangement, or an activating point mutation of RAS or BRAF genes that induce a constitutive activation of the MAP kinase pathway. Follicular carcinomas are characterized by the presence of a RAS mutation or of a PAX8-PPARγ rearrangement. Inactivating mutations of the p53 gene are found only in anaplastic thyroid carcinomas.",

keywords = "Oncogen, Thyroid carcinoma",

author = "Ludovic Lacroix and Soria, {Jean Charles} and Bidart, {Jean Michel} and Martin Schlumberger",

year = "2005",

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T1 - Oncogènes et tumeurs de la thyroïde

AU - Lacroix, Ludovic

AU - Soria, Jean Charles

AU - Bidart, Jean Michel

AU - Schlumberger, Martin

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Papillary thyroid carcinomas are characterized in 70% of cases by the presence of either a RET/PTC rearrangement, or an activating point mutation of RAS or BRAF genes that induce a constitutive activation of the MAP kinase pathway. Follicular carcinomas are characterized by the presence of a RAS mutation or of a PAX8-PPARγ rearrangement. Inactivating mutations of the p53 gene are found only in anaplastic thyroid carcinomas.

AB - Papillary thyroid carcinomas are characterized in 70% of cases by the presence of either a RET/PTC rearrangement, or an activating point mutation of RAS or BRAF genes that induce a constitutive activation of the MAP kinase pathway. Follicular carcinomas are characterized by the presence of a RAS mutation or of a PAX8-PPARγ rearrangement. Inactivating mutations of the p53 gene are found only in anaplastic thyroid carcinomas.

KW - Oncogen

KW - Thyroid carcinoma

UR - http://www.scopus.com/inward/record.url?scp=13744255423&partnerID=8YFLogxK

M3 - Article 'review'

C2 - 15689324

AN - SCOPUS:13744255423

SN - 0007-4551

VL - 92

SP - 37

EP - 43

JO - Bulletin du Cancer

JF - Bulletin du Cancer

IS - 1

ER -