Paraneoplastic syndromes in cancers of unknown primary: An unknown field for oncologists

Titre traduit de la contribution: Les syndromes paranéoplasiques dans les cancers d'origine inconnue: une mise au point pour les oncologues praticiens

Elie El Rassy, Tarek Assi, Joseph Kattan, Nicholas Pavlidis

    Résultats de recherche: Contribution à un journalBrève enquêteRevue par des pairs

    10 Citations (Scopus)

    Résumé

    Paraneoplastic syndromes are signs or symptoms that result from tissue damage at locations remote from tumour sites. Paraneoplastic syndromes associated with cancer of unknown primary (CUP) are not well recognized as they are rarely reported. These syndromes can impair various organ functions and include endocrine, neurologic, dermatologic, rheumatologic, hematologic and several other system alterations. To our knowledge, the association between the histological CUP type and the paraneoplastic syndrome has never been assessed. In some instances, paraneoplastic syndromes can become the major clinical problems determining survival. However, they can also herald earlier the occurrence of CUP in patients with asymptomatic tumors. In this article, we review the available literature of CUP patients presenting paraneoplastic syndromes by trying to collect all available published cases during the last three decades. One additional goal of this article is to make practicing oncologists aware of the coexistence of paraneoplastic syndromes in patients with CUP.

    Titre traduit de la contributionLes syndromes paranéoplasiques dans les cancers d'origine inconnue: une mise au point pour les oncologues praticiens
    langue originaleAnglais
    Pages (de - à)590-603
    Nombre de pages14
    journalBulletin du Cancer
    Volume106
    Numéro de publication6
    Les DOIs
    étatPublié - 1 juin 2019

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