Parathyroid Glands Hyperplasias Mimicking Medullary Thyroid Carcinoma Metastatic Lymph Nodes on 18F-DOPA PET/CT

Marie Terroir; Serena Grimaldi; Dana Hartl; Sophie Leboulleux; Désirée Deandreis

doi:10.1097/RLU.0000000000002633

Parathyroid Glands Hyperplasias Mimicking Medullary Thyroid Carcinoma Metastatic Lymph Nodes on 18F-DOPA PET/CT

Marie Terroir, Serena Grimaldi, Dana Hartl, Sophie Leboulleux, Désirée Deandreis

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

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Résumé

A pre operatory assessment by neck US, ¹⁸F-DOPA and ¹⁸F-choline PET/CT was performed in a 43-year-old MEN 2A woman affected by hyperparathyroidism and medullary thyroid carcinoma (MTC). On ¹⁸F-DOPA, two thyroid uptakes were analyzed as multifocal MTC and two others in the central neck compartment as MTC metastatic lymph nodes. After surgery, multifocal intra thyroidal MTC and two parathyroid glands hyperplasias were proved without MTC adenopathies. We report a case of rare false positive uptake on ¹⁸F-DOPA. In case of several endocrine diseases coexistence as in MEN 2A, ¹⁸F-DOPA should be carefully analyzed.

langue originale	Anglais
Pages (de - à)	E497-E498
journal	Clinical Nuclear Medicine
Volume	44
Numéro de publication	8
Les DOIs	https://doi.org/10.1097/RLU.0000000000002633
état	Publié - 1 août 2019
Modification externe	Oui

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10.1097/RLU.0000000000002633

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title = "Parathyroid Glands Hyperplasias Mimicking Medullary Thyroid Carcinoma Metastatic Lymph Nodes on 18F-DOPA PET/CT",

abstract = "A pre operatory assessment by neck US, 18F-DOPA and 18F-choline PET/CT was performed in a 43-year-old MEN 2A woman affected by hyperparathyroidism and medullary thyroid carcinoma (MTC). On 18F-DOPA, two thyroid uptakes were analyzed as multifocal MTC and two others in the central neck compartment as MTC metastatic lymph nodes. After surgery, multifocal intra thyroidal MTC and two parathyroid glands hyperplasias were proved without MTC adenopathies. We report a case of rare false positive uptake on 18F-DOPA. In case of several endocrine diseases coexistence as in MEN 2A, 18F-DOPA should be carefully analyzed.",

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AU - Leboulleux, Sophie

AU - Deandreis, Désirée

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AB - A pre operatory assessment by neck US, 18F-DOPA and 18F-choline PET/CT was performed in a 43-year-old MEN 2A woman affected by hyperparathyroidism and medullary thyroid carcinoma (MTC). On 18F-DOPA, two thyroid uptakes were analyzed as multifocal MTC and two others in the central neck compartment as MTC metastatic lymph nodes. After surgery, multifocal intra thyroidal MTC and two parathyroid glands hyperplasias were proved without MTC adenopathies. We report a case of rare false positive uptake on 18F-DOPA. In case of several endocrine diseases coexistence as in MEN 2A, 18F-DOPA should be carefully analyzed.

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