TY - JOUR
T1 - Pediatric aphereses (workshop SFGM-TC)
AU - Chabannon, Christian
AU - Benakli, Malek
AU - Alexandrova, Kamelia
AU - Coze, Carole
AU - Dalle, Jean Hughes
AU - Giraud, Christine
AU - Huynh, Phuong
AU - Kanouni, Tarik
AU - Kanold, Justyna
AU - Lesieur, Isabelle
AU - Levavasseur, Aurélie
AU - Yakoub-Agha, Ibrahim
AU - Baudoux, Etienne
N1 - Publisher Copyright:
© 2024 Société Française du Cancer
PY - 2025/1/1
Y1 - 2025/1/1
N2 - Practice of pediatric aphereses – in particular when caring for low-weight children – differs from the practice of adult aphereses, since pediatric aphereses represent low numbers of procedures, which has practical implications in terms of practical training and retraining for involved healthcare personnel, as needed for habilitation and validation of ongoing competencies. A specific training is mandatory in order to ensure both the child and the staff safety during and after collection, as well as ensure high quality of the collected cell product and that its meets predefined specifications that depend on its intended use. Low and very low-weight children deserve a particular attention for a number of procedural and clinical aspects: the nature and quality of venous accesses to ensure proper operation of the cell separator, management of hemodynamic fluctuations in relation with the relative importance of the extracorporeal blood volume as compared to the total blood volume of the child, risks and clinical manifestations of citrate toxicity, minimization of stress during the procedure that may include but is not limited to pharmacological sedation. The full spectrum of competencies needed to deal with these aspects is rarely present within a single team of healthcare professionals; it most often requires the tight combination of expertise drawing from the collection facility, the pediatric department and possibly the pediatric intensive care unit ward, whether from the same or from different institutions. Interactions must be formalized in a document that accurately describes which category of actors is responsible for each category of acts (prescriptions, decisions), depending on their initial qualifications, specific competencies, and affiliations.
AB - Practice of pediatric aphereses – in particular when caring for low-weight children – differs from the practice of adult aphereses, since pediatric aphereses represent low numbers of procedures, which has practical implications in terms of practical training and retraining for involved healthcare personnel, as needed for habilitation and validation of ongoing competencies. A specific training is mandatory in order to ensure both the child and the staff safety during and after collection, as well as ensure high quality of the collected cell product and that its meets predefined specifications that depend on its intended use. Low and very low-weight children deserve a particular attention for a number of procedural and clinical aspects: the nature and quality of venous accesses to ensure proper operation of the cell separator, management of hemodynamic fluctuations in relation with the relative importance of the extracorporeal blood volume as compared to the total blood volume of the child, risks and clinical manifestations of citrate toxicity, minimization of stress during the procedure that may include but is not limited to pharmacological sedation. The full spectrum of competencies needed to deal with these aspects is rarely present within a single team of healthcare professionals; it most often requires the tight combination of expertise drawing from the collection facility, the pediatric department and possibly the pediatric intensive care unit ward, whether from the same or from different institutions. Interactions must be formalized in a document that accurately describes which category of actors is responsible for each category of acts (prescriptions, decisions), depending on their initial qualifications, specific competencies, and affiliations.
KW - Apheresis
KW - Guidelines
KW - Hematopoietic cell transplantation
KW - Pediatrics
KW - Practice harmonization workshop
KW - SFGM-TC
UR - http://www.scopus.com/inward/record.url?scp=85187577287&partnerID=8YFLogxK
U2 - 10.1016/j.bulcan.2023.12.008
DO - 10.1016/j.bulcan.2023.12.008
M3 - Article
C2 - 38480055
AN - SCOPUS:85187577287
SN - 0007-4551
VL - 112
SP - S125-S134
JO - Bulletin du Cancer
JF - Bulletin du Cancer
IS - 1
ER -