Peritoneal Metastases from Colorectal Cancer: Treatment Principles and Perspectives

Diane Goéré; Isabelle Sourrouille; Maximiliano Gelli; Léonor Benhaim; Matthieu Faron; Charles Honoré

doi:10.1016/j.soc.2018.02.011

Peritoneal Metastases from Colorectal Cancer: Treatment Principles and Perspectives

Diane Goéré, Isabelle Sourrouille, Maximiliano Gelli, Léonor Benhaim, Matthieu Faron, Charles Honoré

Résultats de recherche: Contribution à un journal › Article 'review' › Revue par des pairs

25 Citations (Scopus)

Résumé

Peritoneal metastases are the third most common site of recurrence of colorectal cancer. Diagnosis is difficult and often made at an advanced stage even on imaging. Curative treatment relies on complete cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC), which dramatically improves survival in selected patients. Main prognostic factors are based on the extent of the peritoneal disease and the completeness of surgery. Therefore, identifying patients at high risk of developing peritoneal metastases with the aim of diagnosing and treating patients at an early stage appears crucial. Proactive attitude and prophylactic treatment based on HIPEC are being evaluated on clinical trials.

langue originale	Anglais
Pages (de - à)	563-583
Nombre de pages	21
journal	Surgical Oncology Clinics of North America
Volume	27
Numéro de publication	3
Les DOIs	https://doi.org/10.1016/j.soc.2018.02.011
état	Publié - 1 juil. 2018

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10.1016/j.soc.2018.02.011

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@article{d670be204d644dcf9ee8a9152e5b4f39,

title = "Peritoneal Metastases from Colorectal Cancer: Treatment Principles and Perspectives",

abstract = "Peritoneal metastases are the third most common site of recurrence of colorectal cancer. Diagnosis is difficult and often made at an advanced stage even on imaging. Curative treatment relies on complete cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC), which dramatically improves survival in selected patients. Main prognostic factors are based on the extent of the peritoneal disease and the completeness of surgery. Therefore, identifying patients at high risk of developing peritoneal metastases with the aim of diagnosing and treating patients at an early stage appears crucial. Proactive attitude and prophylactic treatment based on HIPEC are being evaluated on clinical trials.",

keywords = "Carcinomatosis, Colorectal cancer, HIPEC, Peritoneal metastases",

author = "Diane Go{\'e}r{\'e} and Isabelle Sourrouille and Maximiliano Gelli and L{\'e}onor Benhaim and Matthieu Faron and Charles Honor{\'e}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

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doi = "10.1016/j.soc.2018.02.011",

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TY - JOUR

T1 - Peritoneal Metastases from Colorectal Cancer

T2 - Treatment Principles and Perspectives

AU - Goéré, Diane

AU - Sourrouille, Isabelle

AU - Gelli, Maximiliano

AU - Benhaim, Léonor

AU - Faron, Matthieu

AU - Honoré, Charles

PY - 2018/7/1

Y1 - 2018/7/1

N2 - Peritoneal metastases are the third most common site of recurrence of colorectal cancer. Diagnosis is difficult and often made at an advanced stage even on imaging. Curative treatment relies on complete cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC), which dramatically improves survival in selected patients. Main prognostic factors are based on the extent of the peritoneal disease and the completeness of surgery. Therefore, identifying patients at high risk of developing peritoneal metastases with the aim of diagnosing and treating patients at an early stage appears crucial. Proactive attitude and prophylactic treatment based on HIPEC are being evaluated on clinical trials.

AB - Peritoneal metastases are the third most common site of recurrence of colorectal cancer. Diagnosis is difficult and often made at an advanced stage even on imaging. Curative treatment relies on complete cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC), which dramatically improves survival in selected patients. Main prognostic factors are based on the extent of the peritoneal disease and the completeness of surgery. Therefore, identifying patients at high risk of developing peritoneal metastases with the aim of diagnosing and treating patients at an early stage appears crucial. Proactive attitude and prophylactic treatment based on HIPEC are being evaluated on clinical trials.

KW - Carcinomatosis

KW - Colorectal cancer

KW - HIPEC

KW - Peritoneal metastases

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DO - 10.1016/j.soc.2018.02.011

M3 - Review article

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AN - SCOPUS:85048838175

SN - 1055-3207

VL - 27

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JO - Surgical Oncology Clinics of North America

JF - Surgical Oncology Clinics of North America

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