TY - JOUR
T1 - Physiology and pathology of an immunoendocrine feedback loop
AU - Kroemer, Guido
AU - Brezinschek, Hans Peter
AU - Faessler, Reinhard
AU - Schauenstein, Konrad
AU - Wick, Georg
N1 - Funding Information:
This work was supported by the Austrian Research Council (grant no. S-41/05) and by the Jubilaeumsfondso f the Austrian National Bank (No. 2784).
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Research in autoimmunity has tended to focus on lymphocytes and their products at the expense of other factors that also contribute to the development of disease. Here, Guido Kroemer and colleagues stress that aberrations in immunoendocrinological communication may also be involved in autoaggression. They propose that in the Obese strain of chickens with spontaneous autoimmune thyroiditis, a defect in the regulation of corticosterone by immune signals can be implicated in immune hyperreactivity.
AB - Research in autoimmunity has tended to focus on lymphocytes and their products at the expense of other factors that also contribute to the development of disease. Here, Guido Kroemer and colleagues stress that aberrations in immunoendocrinological communication may also be involved in autoaggression. They propose that in the Obese strain of chickens with spontaneous autoimmune thyroiditis, a defect in the regulation of corticosterone by immune signals can be implicated in immune hyperreactivity.
UR - http://www.scopus.com/inward/record.url?scp=0023925575&partnerID=8YFLogxK
U2 - 10.1016/0167-5699(88)91289-3
DO - 10.1016/0167-5699(88)91289-3
M3 - Article
C2 - 3256322
AN - SCOPUS:0023925575
SN - 0167-5699
VL - 9
SP - 163
EP - 165
JO - Immunology Today
JF - Immunology Today
IS - 6
ER -