Prédisposition génétique aux cancers du sein et de l'ovaire: Diagnostic moléculaire et conséquences

S. Delaloge; L. Albiges; B. Bressac—de Paillerets; A. Chompret

doi:10.1007/s10269-006-0361-y

Prédisposition génétique aux cancers du sein et de l'ovaire: Diagnostic moléculaire et conséquences

S. Delaloge, L. Albiges, B. Bressac—de Paillerets, A. Chompret

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.

Titre traduit de la contribution	Genetic predisposition to breast and ovarian cancer: Molecular diagnosis and consequences
langue originale	Français
Pages (de - à)	213-218
Nombre de pages	6
journal	Oncologie
Volume	8
Numéro de publication	3
Les DOIs	https://doi.org/10.1007/s10269-006-0361-y
état	Publié - 1 janv. 2006

mots-clés

BRCA1
BRCA2
Breast cancer
Ovarian cancer
Predisposition

Accès au document

10.1007/s10269-006-0361-y

Autres fichiers et liens

Lien vers la publication dans Scopus

Contient cette citation

@article{52ceb851cd114b8695867ba6ff5675a0,

title = "Pr{\'e}disposition g{\'e}n{\'e}tique aux cancers du sein et de l'ovaire: Diagnostic mol{\'e}culaire et cons{\'e}quences",

abstract = "The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.",

keywords = "BRCA1, BRCA2, Breast cancer, Ovarian cancer, Predisposition",

author = "S. Delaloge and L. Albiges and {Bressac—de Paillerets}, B. and A. Chompret",

year = "2006",

month = jan,

day = "1",

doi = "10.1007/s10269-006-0361-y",

language = "Fran{\c c}ais",

volume = "8",

pages = "213--218",

journal = "Oncologie",

issn = "1292-3818",

number = "3",

}

TY - JOUR

T1 - Prédisposition génétique aux cancers du sein et de l'ovaire

T2 - Diagnostic moléculaire et conséquences

AU - Delaloge, S.

AU - Albiges, L.

AU - Bressac—de Paillerets, B.

AU - Chompret, A.

PY - 2006/1/1

Y1 - 2006/1/1

N2 - The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.

AB - The molecular diagnosis of a genetic predisposition to breast cancer is now routinely available. BRCA1 and BRCA2 deleterious germline mutations confer very high risks of breast (80% by age 70 years) and ovarian cancer (15-40%). This justifies specific measures of screening, prevention and specific specialized care. The indications, methods and practical consequences of the diagnosis of a genetic predisposition are summarized, and specific care measures presented.

KW - BRCA1

KW - BRCA2

KW - Breast cancer

KW - Ovarian cancer

KW - Predisposition

UR - http://www.scopus.com/inward/record.url?scp=33745118340&partnerID=8YFLogxK

U2 - 10.1007/s10269-006-0361-y

DO - 10.1007/s10269-006-0361-y

M3 - Article

AN - SCOPUS:33745118340

SN - 1292-3818

VL - 8

SP - 213

EP - 218

JO - Oncologie

JF - Oncologie

IS - 3

ER -