Résumé
Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor, secondary to occupational asbestos exposure. Clinical and radiological signs are unspecific. The diagnosis of MPM is based on histology on biopsies best obtained by thoracoscopy. Prophylactic irradiation of chest scars and drains is validated by French guidelines. Surgery, extrapleural pneumonectomy or pleurectomy/decortication, is not recommended outside a clinical trial. Firstline chemotherapy with pemetrexed remains the standard treatment. Bevacizumab is currently tested in an ongoing randomized phase 3 trial, MAPS, ending in late 2013.
Titre traduit de la contribution | Management of malignant pleural mesothelioma in 2013 |
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langue originale | Français |
Pages (de - à) | 447-451 |
Nombre de pages | 5 |
journal | Revue des Maladies Respiratoires Actualites |
Volume | 5 |
Numéro de publication | 5 |
Les DOIs | |
état | Publié - 1 janv. 2013 |
mots-clés
- Asbestosis
- Diagnosis
- Mesothelioma
- Pleura
- Treatment