Prognostic value of neural invasion in rectal carcinoma: A multivariate analysis on 339 patients with curative resection

C. Bognel; C. Rekacewicz; H. Mankarios; J. P. Pignon; D. Elias; P. Duvillard; M. Prade; M. Ducreux; J. Kac; P. Rougier; F. Eschwège; P. Lasser

doi:10.1016/0959-8049(95)00077-1

Prognostic value of neural invasion in rectal carcinoma: A multivariate analysis on 339 patients with curative resection

C. Bognel, C. Rekacewicz, H. Mankarios, J. P. Pignon, D. Elias, P. Duvillard, M. Prade, M. Ducreux, J. Kac, P. Rougier, F. Eschwège, P. Lasser

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

35 Citations (Scopus)

Résumé

To determine whether neural invasion or other clinico-pathological factors are prognostic, we performed a retrospective study on 339 rectal carcinomas. The overall 5-year survival was 62%. In the multivariate analysis, age over 60 years, a distance from the anal verge of less than 6 cm, the number of positive lymph nodes, neural invasion and tumour penetration were found to be prognostic. A scoring system identified five prognostic groups of patients. Neural invasion is an independent prognostic factor in our scoring system and it is suggested that this parameter should be taken into consideration for postsurgical treatment.

langue originale	Anglais
Pages (de - à)	894-898
Nombre de pages	5
journal	European Journal of Cancer
Volume	31
Numéro de publication	6
Les DOIs	https://doi.org/10.1016/0959-8049(95)00077-1
état	Publié - 1 janv. 1995

Accès au document

10.1016/0959-8049(95)00077-1

Autres fichiers et liens

Lien vers la publication dans Scopus

Contient cette citation

Bognel, C., Rekacewicz, C., Mankarios, H., Pignon, J. P., Elias, D., Duvillard, P., Prade, M., Ducreux, M., Kac, J., Rougier, P., Eschwège, F., & Lasser, P. (1995). Prognostic value of neural invasion in rectal carcinoma: A multivariate analysis on 339 patients with curative resection. European Journal of Cancer, 31(6), 894-898. https://doi.org/10.1016/0959-8049(95)00077-1

@article{5888d8a23915490a8d1ed57a0c5249f2,

title = "Prognostic value of neural invasion in rectal carcinoma: A multivariate analysis on 339 patients with curative resection",

abstract = "To determine whether neural invasion or other clinico-pathological factors are prognostic, we performed a retrospective study on 339 rectal carcinomas. The overall 5-year survival was 62%. In the multivariate analysis, age over 60 years, a distance from the anal verge of less than 6 cm, the number of positive lymph nodes, neural invasion and tumour penetration were found to be prognostic. A scoring system identified five prognostic groups of patients. Neural invasion is an independent prognostic factor in our scoring system and it is suggested that this parameter should be taken into consideration for postsurgical treatment.",

keywords = "multivariate analysis, neural invasion, prognostic study, rectal carcinoma",

author = "C. Bognel and C. Rekacewicz and H. Mankarios and Pignon, {J. P.} and D. Elias and P. Duvillard and M. Prade and M. Ducreux and J. Kac and P. Rougier and F. Eschw{\`e}ge and P. Lasser",

note = "Funding Information: Acknowledgements----This work was supported by the Michaelsen Foundation, the Harboe Foundation, the Danish King Christian, the X Foundation and the Danish Cancer Society.",

year = "1995",

month = jan,

day = "1",

doi = "10.1016/0959-8049(95)00077-1",

language = "English",

volume = "31",

pages = "894--898",

journal = "European Journal of Cancer",

issn = "0959-8049",

number = "6",

}

Bognel, C, Rekacewicz, C, Mankarios, H, Pignon, JP, Elias, D, Duvillard, P, Prade, M, Ducreux, M, Kac, J, Rougier, P, Eschwège, F & Lasser, P 1995, 'Prognostic value of neural invasion in rectal carcinoma: A multivariate analysis on 339 patients with curative resection', European Journal of Cancer, VOL. 31, Numéro 6, p. 894-898. https://doi.org/10.1016/0959-8049(95)00077-1

TY - JOUR

T1 - Prognostic value of neural invasion in rectal carcinoma

T2 - A multivariate analysis on 339 patients with curative resection

AU - Bognel, C.

AU - Rekacewicz, C.

AU - Mankarios, H.

AU - Pignon, J. P.

AU - Elias, D.

AU - Duvillard, P.

AU - Prade, M.

AU - Ducreux, M.

AU - Kac, J.

AU - Rougier, P.

AU - Eschwège, F.

AU - Lasser, P.

N1 - Funding Information: Acknowledgements----This work was supported by the Michaelsen Foundation, the Harboe Foundation, the Danish King Christian, the X Foundation and the Danish Cancer Society.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - To determine whether neural invasion or other clinico-pathological factors are prognostic, we performed a retrospective study on 339 rectal carcinomas. The overall 5-year survival was 62%. In the multivariate analysis, age over 60 years, a distance from the anal verge of less than 6 cm, the number of positive lymph nodes, neural invasion and tumour penetration were found to be prognostic. A scoring system identified five prognostic groups of patients. Neural invasion is an independent prognostic factor in our scoring system and it is suggested that this parameter should be taken into consideration for postsurgical treatment.

AB - To determine whether neural invasion or other clinico-pathological factors are prognostic, we performed a retrospective study on 339 rectal carcinomas. The overall 5-year survival was 62%. In the multivariate analysis, age over 60 years, a distance from the anal verge of less than 6 cm, the number of positive lymph nodes, neural invasion and tumour penetration were found to be prognostic. A scoring system identified five prognostic groups of patients. Neural invasion is an independent prognostic factor in our scoring system and it is suggested that this parameter should be taken into consideration for postsurgical treatment.

KW - multivariate analysis

KW - neural invasion

KW - prognostic study

KW - rectal carcinoma

UR - http://www.scopus.com/inward/record.url?scp=0007932972&partnerID=8YFLogxK

U2 - 10.1016/0959-8049(95)00077-1

DO - 10.1016/0959-8049(95)00077-1

M3 - Article

C2 - 7646917

AN - SCOPUS:0007932972

SN - 0959-8049

VL - 31

SP - 894

EP - 898

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 6

ER -