Pseudodiabetes—not a contraindication for metabolic interventions

José Manuel Bravo-San Pedro, Valentina Sica, Guido Kroemer

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    Résumé

    Type-2 diabetes is characterized by glycosuria, hyperglycemia, glucose intolerance, hyperinsulinemia, and insulin resistance. One or several among these alterations are also found after starvation, ketogenic diet, and pharmacological treatment with rapamycin or antibody-mediated neutralization of the obesogenic factor ACBP/DBI. Thus, a variety of metabolic interventions that improve metabolic health can induce a transient state of “pseudo-diabetes”.

    langue originaleAnglais
    Numéro d'article765
    journalCell Death and Disease
    Volume10
    Numéro de publication10
    Les DOIs
    étatPublié - 1 oct. 2019

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