TY - JOUR
T1 - Pseudodiabetes—not a contraindication for metabolic interventions
AU - Bravo-San Pedro, José Manuel
AU - Sica, Valentina
AU - Kroemer, Guido
N1 - Publisher Copyright:
© 2019, The Author(s).
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Type-2 diabetes is characterized by glycosuria, hyperglycemia, glucose intolerance, hyperinsulinemia, and insulin resistance. One or several among these alterations are also found after starvation, ketogenic diet, and pharmacological treatment with rapamycin or antibody-mediated neutralization of the obesogenic factor ACBP/DBI. Thus, a variety of metabolic interventions that improve metabolic health can induce a transient state of “pseudo-diabetes”.
AB - Type-2 diabetes is characterized by glycosuria, hyperglycemia, glucose intolerance, hyperinsulinemia, and insulin resistance. One or several among these alterations are also found after starvation, ketogenic diet, and pharmacological treatment with rapamycin or antibody-mediated neutralization of the obesogenic factor ACBP/DBI. Thus, a variety of metabolic interventions that improve metabolic health can induce a transient state of “pseudo-diabetes”.
UR - http://www.scopus.com/inward/record.url?scp=85073115384&partnerID=8YFLogxK
U2 - 10.1038/s41419-019-2007-1
DO - 10.1038/s41419-019-2007-1
M3 - Comment/debate
C2 - 31601789
AN - SCOPUS:85073115384
SN - 2041-4889
VL - 10
JO - Cell Death and Disease
JF - Cell Death and Disease
IS - 10
M1 - 765
ER -