Pyroptosis - A cell death modality of its kind?

Oliver Kepp, Lorenzo Galluzzi, Laurence Zitvogel, Guido Kroemer

    Résultats de recherche: Contribution à un journalArticle 'review'Revue par des pairs

    121 Citations (Scopus)

    Résumé

    The term "pyroptosis" was originally introduced to describe a particular form of cell death in macrophages, which is induced by bacterial infection, is accompanied by caspase-1 activation and hence leads to the release of pyrogenic interleukins; however, it is still controversial whether pyroptosis - which can also be triggered by nonbacterial pathological stimuli - truly represents a cell death modality on its own or whether it constitutes a special case of apoptosis or necrosis.

    langue originaleAnglais
    Pages (de - à)627-630
    Nombre de pages4
    journalEuropean Journal of Immunology
    Volume40
    Numéro de publication3
    Les DOIs
    étatPublié - 1 mars 2010

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