Redifferentiation-facilitated radioiodine therapy in thyroid cancer

Livia Lamartina, Nadège Anizan, Corinne Dupuy, Sophie Leboulleux, Martin Schlumberger

    Résultats de recherche: Contribution à un journalArticle 'review'Revue par des pairs

    34 Citations (Scopus)

    Résumé

    Based on experimental data, the inhibition of the MAPkinase pathway in patients with radioiodine-refractory thyroid cancer was capable of inducing a redifferentiation. Preliminary data obtained in a small series of patients were encouraging and this strategy might become an alternative treatment in those patients with a druggable mutation that induces a stimulation of the MAP kinase pathway. This is an active field of research to answer many still unresolved questions.

    langue originaleAnglais
    Pages (de - à)T179-T191
    journalEndocrine-Related Cancer
    Volume28
    Numéro de publication10
    Les DOIs
    étatPublié - 1 oct. 2021

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