Response of an ovarian granulosa cell tumor with everolimus and exemestane after initial response to letrozole

Tarek Assi, Hampig R. Kourie, Elie El Rassy, Tania Moussa, Joseph Kattan

    Résultats de recherche: Contribution à un journalArticleRevue par des pairs

    2 Citations (Scopus)

    Résumé

    Granulosa cell tumors of the ovaries (GCTO), the most common sex cord tumors of the female genitalia, are characterized by a remarkably favorable prognosis but tend to recur even after several years of follow-up. Standard approach to manage these relapsing tumors is almost inexistent and physicians' choice is most commonly based on his/her personal expertise. Recently, the use of hormone therapy in GCTO has induced prolonged response and survival. In this case report, we report the first successful use of everolimus in the combination of exemestane to reverse the resistance to hormonal therapy with letrozole in a 53-year-old woman with GCTO.

    langue originaleAnglais
    Pages (de - à)931-933
    Nombre de pages3
    journalAnti-Cancer Drugs
    Volume28
    Numéro de publication8
    Les DOIs
    étatPublié - 1 janv. 2017

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