Results of interval debulking surgery in advanced stage ovarian cancer: An exposed-non-exposed study

P. Morice; D. Brehier-Ollive; A. Rey; D. Atallah; C. Lhommé; P. Pautier; C. Pomel; S. Camatte; P. Duvillard; D. Castaigne

doi:10.1093/annonc/mdg003

Results of interval debulking surgery in advanced stage ovarian cancer: An exposed-non-exposed study

P. Morice, D. Brehier-Ollive, A. Rey, D. Atallah, C. Lhommé, P. Pautier, C. Pomel, S. Camatte, P. Duvillard, D. Castaigne

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Résumé

Background: To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy. Patients and methods: An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS. Results: Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups. Conclusions: IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.

langue originale	Anglais
Pages (de - à)	74-77
Nombre de pages	4
journal	Annals of Oncology
Volume	14
Numéro de publication	1
Les DOIs	https://doi.org/10.1093/annonc/mdg003
état	Publié - 1 janv. 2003

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10.1093/annonc/mdg003

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title = "Results of interval debulking surgery in advanced stage ovarian cancer: An exposed-non-exposed study",

abstract = "Background: To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy. Patients and methods: An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS. Results: Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups. Conclusions: IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.",

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T2 - An exposed-non-exposed study

AU - Morice, P.

AU - Brehier-Ollive, D.

AU - Rey, A.

AU - Atallah, D.

AU - Lhommé, C.

AU - Pautier, P.

AU - Pomel, C.

AU - Camatte, S.

AU - Duvillard, P.

AU - Castaigne, D.

PY - 2003/1/1

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N2 - Background: To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy. Patients and methods: An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS. Results: Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups. Conclusions: IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.

AB - Background: To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy. Patients and methods: An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS. Results: Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups. Conclusions: IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.

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KW - Interval debulking surgery

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KW - Unresectable tumour

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